Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17554858 | 0.94 | KIF11 (0.36) | KIF11GRIA2GRIA4CYP2A6NSD2 | |
| SCHEMBL17554868 | 0.88 | KIF11 (0.34) | KIF11GRIA2GRIA4CYP2A6NSD2 | |
| SCHEMBL1946686 | 0.87 | KIF11 (0.33) | KIF11GRIA2GRIA4CYP2A6 | |
| SCHEMBL1950423 | 0.87 | KIF11 (0.33) | KIF11GRIA2GRIA4CYP2A6 | |
| SCHEMBL2107804 | 0.81 | KIF11 (0.35) | KIF11GRIA2GRIA4CYP2A6NSD2 | |
| SCHEMBL1951272 | 0.81 | KIF11 (0.35) | KIF11GRIA2GRIA4CYP2A6 | |
| SCHEMBL1946692 | 0.81 | KIF11 (0.35) | KIF11GRIA2GRIA4CYP2A6 | |
| SCHEMBL17554960 | 0.80 | AKR1C3 (0.35) | AR | |
| SCHEMBL17554876 | 0.79 | — | — | |
| SCHEMBL17554954 | 0.79 | HEXA (0.30) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120556-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-09 | — | — | EP | disclosed |