SCHEMBL2107804

SCHEMBL2107804

CCc1[c]c(I)cc(C(F)(C(F)(F)F)C(F)(F)F)c1-c1ccc(C#N)cc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.35
CYP2A6 P11509 1/20 0.33
GRIA2 P42262 1/20 0.31
GRIA4 P48058 1/20 0.31
NSD2 O96028 1/20 0.31
CYP11B2 P19099 1/20 0.30
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17554858 0.86 KIF11 (0.36) KIF11CYP2A6GRIA2GRIA4NSD2
SCHEMBL1946386 0.83 KIF11 (0.39) KIF11CYP11B2
SCHEMBL1948236 0.81 KIF11 (0.38) KIF11
SCHEMBL17555010 0.81 KIF11 (0.34) KIF11CYP2A6GRIA2GRIA4NSD2
SCHEMBL17554868 0.81 KIF11 (0.34) KIF11CYP2A6GRIA2GRIA4NSD2
SCHEMBL1946692 0.81 KIF11 (0.35) KIF11CYP2A6GRIA2GRIA4CYP11B2
SCHEMBL2105359 0.79 AKR1C3 (0.36)
SCHEMBL1951332 0.78 KIF11 (0.37) KIF11
SCHEMBL2106428 0.76 KIF11 (0.34) KIF11TSHRHSD17B10
SCHEMBL1948959 0.76 KIF11 (0.40) KIF11NSD2CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8163804-B2 Composition for preventing harmful organisms MITSUI CHEMICALS, INC. (JP) 2012-04-24 US disclosed