Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.31 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | SELE | P16581 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1755767 | 0.92 | PTGER4 (0.38) | PTGER4FKBP1AADRB3KCNH2CREBBP | |
| SCHEMBL8264747 | 0.92 | GRM2 (0.37) | PTGER4 | |
| SCHEMBL481084 | 0.89 | MRGPRX4 (0.35) | PTGER4KCNH2PTGER1 | |
| SCHEMBL1755708 | 0.87 | GRM2 (0.39) | PTGER4KCNH2CREBBP | |
| SCHEMBL1755729 | 0.86 | GRM2 (0.39) | — | |
| SCHEMBL8264743 | 0.83 | L3MBTL1 (0.36) | PTGER4FKBP1AADRB3CREBBPICAM1 | |
| SCHEMBL480832 | 0.83 | PTGER4 (0.43) | PTGER4CREBBPPTGER1 | |
| SCHEMBL10244891 | 0.83 | PTGER4 (0.38) | PTGER4FKBP1AADRB3CREBBPFKBP4 | |
| SCHEMBL481416 | 0.83 | PTGER4 (0.39) | PTGER4 | |
| SCHEMBL481096 | 0.82 | GRM2 (0.36) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441762-A1 | Potentiators of Glutamate Receptors | Eli Lilly and Company (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2006057870-A1 | POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |