Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | IL1RN | P18510 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28407772 | 0.90 | FFAR4 (0.57) | FFAR4ALDH1A1PKMCA2MAPT | |
| SCHEMBL15647438 | 0.87 | KMT2A (0.61) | FFAR4ALDH1A1MEN1KMT2APKM | |
| SCHEMBL9749511 | 0.83 | FFAR4 (0.71) | FFAR4ALDH1A1MEN1KMT2APKM | |
| SCHEMBL6570574 | 0.83 | ALDH1A1 (0.72) | FFAR4ALDH1A1MEN1KMT2APKM | |
| SCHEMBL8026293 | 0.83 | FFAR4 (0.71) | FFAR4ALDH1A1MEN1KMT2APKM | |
| SCHEMBL10618991 | 0.83 | FFAR4 (1.00) | FFAR4ALDH1A1MEN1KMT2APKM | |
| SCHEMBL4968417 | 0.83 | FFAR4 (0.71) | FFAR4ALDH1A1MEN1KMT2APKM | |
| SCHEMBL9906419 | 0.81 | FFAR4 (0.67) | FFAR4ALDH1A1MEN1KMT2APKM | |
| SCHEMBL10610753 | 0.80 | MAPT (0.60) | FFAR4ALDH1A1MEN1KMT2ACA2 | |
| SCHEMBL17978495 | 0.80 | FFAR4 (0.66) | FFAR4ALDH1A1MEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884866-B2 | Immunomodulators and immunomodulator conjugates | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-02-06 | — | — | US | disclosed |
| US-20160068533-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2016-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068533-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | CD40, CD47, FCGRT | FFAR4 1402/4885ALDH1A1 197/4885MEN1 2185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.