Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.71 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.59 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.59 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.59 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.58 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.58 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.56 |
| ▸ | CRHBP | P24387 | 2/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27809726 | 0.87 | VCAM1 (0.61) | FFAR4HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL3619380 | 0.87 | SLC25A1 (0.67) | FFAR4HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL7371667 | 0.85 | KMT2A (0.62) | FFAR4DNMT1DNMT3ASLC25A1KMT2A | |
| SCHEMBL5225915 | 0.84 | VCAM1 (0.64) | FFAR4HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL6570574 | 0.83 | ALDH1A1 (0.72) | FFAR4KMT2AMEN1MAPTLMNA | |
| SCHEMBL8026293 | 0.83 | FFAR4 (0.71) | FFAR4DNMT1DNMT3AKMT2AMEN1 | |
| SCHEMBL4968417 | 0.83 | FFAR4 (0.71) | FFAR4KMT2AMEN1MAPTLMNA | |
| SCHEMBL17557158 | 0.83 | FFAR4 (0.71) | FFAR4KMT2AMEN1MAPTLMNA | |
| SCHEMBL10618991 | 0.83 | FFAR4 (1.00) | FFAR4KMT2AMEN1MAPTLMNA | |
| SCHEMBL5059972 | 0.83 | KMT2A (0.57) | FFAR4HSPD1PTPN2PTPN1PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1329382-C | Novel arylsusfonamide compounds for treatment of obesity, type II diabetes and CNS-disorders | BIOVITRUM AB (SE) | 2007-08-01 | — | — | CN | disclosed |
| CN-1531531-A | Novel arylsulfonamide compounds for the treatment of obesity, type II diabetes and CNS-disorders | �Ȱ�ά����ķ�ɷݹ�˾ | 2004-09-22 | — | — | CN | disclosed |
| US-5132461-A | Process for the production of 4-[ethyl-(2'-hydroxyethyl)-amino]-1-[(2'-hydroxyethyl)-amino]-2-nitro-benzene | WELLA AKTIENGESELLSCHAFT (DE) | 1992-07-21 | — | — | US | disclosed |
| US-4900869-A | Process for the production of 4-[ethyl-(2'-hydroxyethyl)-amino]-1-[(2'-hydroxyethyl)-amino]-2-nitrobenzene | Wella, Aktiengesellschaft (DE) | 1990-02-13 | — | — | US | disclosed |
| US-3978061-A | HAIR DYES | L'OREAL (FR) | 1976-08-31 | — | — | US | disclosed |