Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.30 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL480876 | 0.89 | PPARG (0.34) | PTGER4PPARGPPARDPPARACYSLTR1 | |
| SCHEMBL480875 | 0.89 | PPARG (0.34) | PTGER4PPARGPPARDPPARACYSLTR1 | |
| SCHEMBL480877 | 0.89 | PPARG (0.34) | PTGER4PPARGPPARDPPARACYSLTR1 | |
| SCHEMBL1755706 | 0.82 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2TBXAS1LTB4RLTB4R2 | |
| SCHEMBL1755728 | 0.78 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2TBXAS1LTB4RLTB4R2 | |
| SCHEMBL13645751 | 0.78 | PTGER4 (0.35) | PTGER4CYSLTR1CYSLTR2TBXAS1LTB4R | |
| SCHEMBL1755767 | 0.78 | PTGER4 (0.38) | PTGER4ADRB3CYSLTR1FKBP1AMAPT | |
| SCHEMBL8264743 | 0.78 | L3MBTL1 (0.36) | PTGER4ADRB3CYSLTR1FKBP1AMEN1 | |
| SCHEMBL10244891 | 0.77 | PTGER4 (0.38) | PTGER4ADRB3CYSLTR1FKBP1AMAPT | |
| SCHEMBL481296 | 0.76 | CYSLTR1 (0.42) | CYSLTR1CYSLTR2TBXAS1LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441762-A1 | Potentiators of Glutamate Receptors | Eli Lilly and Company (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2006057870-A1 | POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |