SCHEMBL17558102

SCHEMBL17558102

CCCCCC=CCC=CCCCCCCCCOc1ccc(CO)c(OCCCCCCCCC=CCC=CCCCCC)c1

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
CNR2 P34972 5/20 0.47
CNR1 P21554 5/20 0.47
ALDH1A1 P00352 2/20 0.45
NR5A1 Q13285 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17558100 1.00 TSHR (0.47) TSHRCNR2CNR1ALDH1A1NR5A1
SCHEMBL17558159 0.90 CNR1 (0.47) CNR2CNR1ALDH1A1NR5A1
SCHEMBL17558160 0.90 CNR1 (0.47) CNR2CNR1ALDH1A1NR5A1
SCHEMBL15522362 0.89 NR5A1 (0.53) TSHRCNR2ALDH1A1NR5A1MEN1
SCHEMBL30775079 0.89 NR5A1 (0.53) TSHRCNR2ALDH1A1NR5A1MEN1
SCHEMBL3682775 0.89 NR5A1 (0.53) TSHRCNR2ALDH1A1NR5A1MEN1
SCHEMBL135802 0.89 NR5A1 (0.53) TSHRCNR2ALDH1A1NR5A1MEN1
SCHEMBL31442492 0.82 PPARA (0.49) MEN1KMT2A
SCHEMBL17577604 0.82 CNR1 (0.48) CNR2CNR1
SCHEMBL17558117 0.81 MGLL (0.54) CNR2CNR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3188760-B1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2023-12-06 EP disclosed
US-10844002-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2020-11-24 US disclosed
US-20190002393-A1 Lipids and Lipid Compositions for the Delivery of Active Agents NOVARTIS AG (CH) 2019-01-03 US disclosed
US-10125092-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2018-11-13 US disclosed
US-20170275243-A1 Lipids and Lipid Compositions for the Delivery of Active Agents NOVARTIS AG (CH) 2017-09-28 US disclosed
EP-3188760-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS Novartis AG (CH) 2017-07-12 EP disclosed
WO-2016037053-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2016-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10844002-B2 Lipids and lipid compositions for the delivery of active agents LRAT, LIPA, LPAR1 TSHR 584/4885CNR2 2131/4885CNR1 1487/4885
US-20170275243-A1 Lipids and Lipid Compositions for the Delivery of Active Agents LRAT, LPAR4, LPAR1 TSHR 591/4885CNR2 2153/4885CNR1 1519/4885
US-10125092-B2 Lipids and lipid compositions for the delivery of active agents LRAT, LPAR4, LPAR1 TSHR 591/4885CNR2 2153/4885CNR1 1519/4885
US-20190002393-A1 Lipids and Lipid Compositions for the Delivery of Active Agents LRAT, LIPA, LPAR1 TSHR 584/4885CNR2 2131/4885CNR1 1487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.