SCHEMBL135802

SCHEMBL135802

CCCCCCCCCCCCCCCCCCCCCCOc1ccc(CO)c(OCCCCCCCCCCCCCCCCCCCCCC)c1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.53
TSHR P16473 3/20 0.52
CNR2 P34972 5/20 0.51
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
KMT2A Q03164 1/20 0.50
TP53 P04637 1/20 0.47
PLA2G4B P0C869 1/20 0.46
LTA4H P09960 1/20 0.46
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46
PTPN11 Q06124 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15522362 1.00 NR5A1 (0.53) NR5A1TSHRCNR2MEN1ALDH1A1
SCHEMBL3682775 1.00 NR5A1 (0.53) NR5A1TSHRCNR2MEN1ALDH1A1
SCHEMBL30775079 1.00 NR5A1 (0.53) NR5A1TSHRCNR2MEN1ALDH1A1
SCHEMBL2017497 0.91 CNR2 (0.53) NR5A1TSHRCNR2MEN1ALDH1A1
SCHEMBL17558102 0.89 TSHR (0.47) NR5A1TSHRCNR2MEN1ALDH1A1
SCHEMBL17558100 0.89 TSHR (0.47) NR5A1TSHRCNR2MEN1ALDH1A1
SCHEMBL17558130 0.88 CNR2 (0.56) TSHRCNR2MEN1ALDH1A1KMT2A
SCHEMBL27088421 0.86 TSHR (0.59) NR5A1TSHRCNR2MEN1ALDH1A1
SCHEMBL25254779 0.86 CNR2 (0.44) NR5A1TSHRCNR2MEN1ALDH1A1
SCHEMBL25297144 0.86 CNR2 (0.44) NR5A1TSHRCNR2MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12454526-B2 Method for producing pyrrole-imidazole (poly)amide KANEKA CORPORATION (JP) 2025-10-28 US claimed
EP-3778621-B1 PEPTIDE SYNTHESIS METHOD JITSUBO CO LTD (JP) 2023-08-23 EP claimed
US-9353148-B2 Method for producing peptide AJINOMOTO CO., INC. (JP) 2016-05-31 US claimed
US-9353147-B2 Method for producing peptide AJINOMOTO CO., INC. (JP) 2016-05-31 US claimed
US-20140088291-A1 METHOD FOR PRODUCING PEPTIDE AJINOMOTO CO., INC. (JP) 2014-03-27 US claimed
US-20140080999-A1 METHOD FOR PRODUCING PEPTIDE AJINOMOTO CO., INC. (JP) 2014-03-20 US claimed
US-12454526-B2 Method for producing pyrrole-imidazole (poly)amide KANEKA CORPORATION (JP) 2025-10-28 US disclosed
US-12351601-B2 Method for producing peptide continuously AJINOMOTO CO., INC. (JP) 2025-07-08 US disclosed
WO-2025122535-A2 LIQUID PHASE PEPTIDE SYNTHESIS METHODS AMGEN INC. (US) 2025-06-12 WO disclosed
US-20250188118-A1 LIQUID PHASE PEPTIDE SYNTHESIS METHODS AMGEN INC. (US) 2025-06-12 US disclosed
US-12172946-B2 Compound containing diphenylmethane structure and use thereof GUANGZHOU TROJAN PHARMATEC LTD. (CN) 2024-12-24 US disclosed
CN-114409564-B Compound containing trityl structure and application thereof 广州同隽医药科技有限公司 2024-04-26 CN disclosed
US-11939404-B2 Method for producing cyclized peptide having intramolecular S-S bond AJINOMOTO CO., INC. (JP) 2024-03-26 US disclosed
EP-2612845-A1 AROMATIC COMPOUND CONTAINING SPECIFIC BRANCH Ajinomoto Co., Inc. (JP) 2013-07-10 EP disclosed
US-20120296074-A1 PRODUCTION METHOD OF OLIGONUCLEOTIDE AJINOMOTO CO., INC. (JP) 2012-11-22 US disclosed
EP-2518041-A1 BENZYL COMPOUND Ajinomoto Co., Inc. (JP) 2012-10-31 EP disclosed
US-20120059149-A1 BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND AJINOMOTO CO. INC. (JP) 2012-03-08 US disclosed
US-20110160433-A1 BENZYLIC COMPOUND AJINOMOTO CO., INC. (JP) 2011-06-30 US disclosed
US-20100029904-A1 Carrier for Separation, Method for Separation of Compound, and Method for Synthesis of Peptide Using the Carrier JITSUBO CO., LTD. (JP) 2010-02-04 US disclosed
EP-1927584-A1 CARRIER FOR SEPARATION, METHOD FOR SEPARATION OF COMPOUND, AND METHOD FOR SYNTHESIS OF PEPTIDE USING THE CARRIER National University Corporation Tokyo University of Agriculture and Technology (JP) 2008-06-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188118-A1 LIQUID PHASE PEPTIDE SYNTHESIS METHODS VIP, RNGTT, SSU72 NR5A1 1636/4885TSHR 2281/4885CNR2 4682/4885
US-20110160433-A1 BENZYLIC COMPOUND VIP, NGLY1, FURIN NR5A1 1975/4885TSHR 2705/4885CNR2 2139/4885
US-20100029904-A1 Carrier for Separation, Method for Separation of Compound, and Method for Synthesis of Peptide Using the Carrier CCKBR, CCKAR, VIP NR5A1 1211/4885TSHR 815/4885CNR2 1592/4885
US-11939404-B2 Method for producing cyclized peptide having intramolecular S-S bond SPPL2B, PTMS, VIP NR5A1 1233/4885TSHR 1502/4885CNR2 4671/4885
US-20140080999-A1 METHOD FOR PRODUCING PEPTIDE VIP, ANPEP, NPPA NR5A1 2972/4885TSHR 2603/4885CNR2 4329/4885
US-20120059149-A1 BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND VIP, BCAT2, IAPP NR5A1 765/4885TSHR 2322/4885CNR2 4852/4885
US-20140088291-A1 METHOD FOR PRODUCING PEPTIDE ANPEP, NPPA, LNPEP NR5A1 2104/4885TSHR 1168/4885CNR2 4129/4885
US-12172946-B2 Compound containing diphenylmethane structure and use thereof PEPD, VIP, DNPEP NR5A1 1603/4885TSHR 2038/4885CNR2 4546/4885
US-12351601-B2 Method for producing peptide continuously VIP, NPPA, NGLY1 NR5A1 2347/4885TSHR 1885/4885CNR2 4197/4885
US-20120296074-A1 PRODUCTION METHOD OF OLIGONUCLEOTIDE RNGTT, POLM, RNMT NR5A1 2010/4885TSHR 1572/4885CNR2 4676/4885
US-12454526-B2 Method for producing pyrrole-imidazole (poly)amide DDC, PAM, AADAC NR5A1 4702/4885TSHR 3668/4885CNR2 2481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.