SCHEMBL17558129

SCHEMBL17558129

CCCCCCCCCC(=O)OCCCCCCCCOc1ccc(OCCCCCOC(=O)CCC(OCCCCCCCC)OCCCCCCCC)c(C=O)c1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.44
PPARG P37231 3/20 0.43
PPARA Q07869 1/20 0.43
KDM4E B2RXH2 1/20 0.41
RAB9A P51151 1/20 0.41
PTGES O14684 1/20 0.40
ALOX5 P09917 1/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
DGKA P23743 1/20 0.40
PLA2G4B P0C869 1/20 0.39
THRA P10827 2/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17558144 1.00 CNR2 (0.44) CNR2PPARGPPARAKDM4ERAB9A
SCHEMBL17577591 0.98 KDM4E (0.42) CNR2PPARGPPARAKDM4ERAB9A
SCHEMBL17558105 0.97 PLA2G4B (0.43) CNR2PPARGPPARAKDM4ERAB9A
SCHEMBL17558140 0.90 DGKA (0.49) CNR2PPARGPPARAPTGESALOX5
SCHEMBL17558092 0.86 CNR2 (0.48) CNR2PPARGPPARAPTGESALOX5
SCHEMBL17558103 0.86 CNR2 (0.48) CNR2PPARGPPARAPTGESALOX5
SCHEMBL17558094 0.86 CNR2 (0.48) CNR2PPARGPPARAPTGESALOX5
SCHEMBL17558132 0.86 CNR2 (0.48) CNR2PPARGPPARAPTGESALOX5
SCHEMBL17558124 0.83 MGLL (0.52) CNR2PPARGPPARATSHRTHRB
SCHEMBL19376406 0.83 MGLL (0.52) CNR2PPARGPPARATSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3188760-B1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2023-12-06 EP disclosed
US-10844002-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2020-11-24 US disclosed
US-10844002-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2020-11-24 US disclosed
US-20190002393-A1 Lipids and Lipid Compositions for the Delivery of Active Agents NOVARTIS AG (CH) 2019-01-03 US disclosed
US-20190002393-A1 Lipids and Lipid Compositions for the Delivery of Active Agents NOVARTIS AG (CH) 2019-01-03 US disclosed
US-10125092-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2018-11-13 US disclosed
US-20170275243-A1 Lipids and Lipid Compositions for the Delivery of Active Agents NOVARTIS AG (CH) 2017-09-28 US disclosed
US-20170275243-A1 Lipids and Lipid Compositions for the Delivery of Active Agents NOVARTIS AG (CH) 2017-09-28 US disclosed
US-20170275243-A1 Lipids and Lipid Compositions for the Delivery of Active Agents NOVARTIS AG (CH) 2017-09-28 US disclosed
EP-3188760-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS Novartis AG (CH) 2017-07-12 EP disclosed
WO-2016037053-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2016-03-10 WO disclosed
WO-2016037053-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2016-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10844002-B2 Lipids and lipid compositions for the delivery of active agents LRAT, LIPA, LPAR1 CNR2 2131/4885PPARG 597/4885PPARA 686/4885
US-20170275243-A1 Lipids and Lipid Compositions for the Delivery of Active Agents LRAT, LPAR4, LPAR1 CNR2 2153/4885PPARG 626/4885PPARA 733/4885
US-10125092-B2 Lipids and lipid compositions for the delivery of active agents LRAT, LPAR4, LPAR1 CNR2 2153/4885PPARG 626/4885PPARA 733/4885
US-20190002393-A1 Lipids and Lipid Compositions for the Delivery of Active Agents LRAT, LIPA, LPAR1 CNR2 2131/4885PPARG 597/4885PPARA 686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.