Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806462 | 0.89 | ALK (0.55) | ALK | |
| SCHEMBL7813080 | 0.83 | ALK (0.54) | ALK | |
| SCHEMBL7806767 | 0.80 | ALK (0.59) | ALK | |
| SCHEMBL1755890 | 0.80 | ALK (0.49) | ALK | |
| SCHEMBL896397 | 0.79 | ALK (0.68) | ALK | |
| SCHEMBL7810032 | 0.78 | ALK (0.58) | ALK | |
| SCHEMBL7815079 | 0.77 | ALK (0.51) | ALK | |
| SCHEMBL7816665 | 0.76 | ALK (0.52) | ALK | |
| SCHEMBL7808626 | 0.76 | ALK (0.66) | ALK | |
| SCHEMBL7820105 | 0.76 | ALK (0.79) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441753-A1 | TETRACYCLIC COMPOUND | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-04-18 | — | — | EP | disclosed |