SCHEMBL17559355

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17559334	0.88	PRMT5 (0.55)	NPSR1PRMT5ALDH1A1HPGDLMNA
	SCHEMBL17559338	0.86	NPSR1 (0.56)	NPSR1PRMT5ALDH1A1HPGDLMNA
	SCHEMBL28274071	0.79	HSD17B10 (0.48)	ALDH1A1HPGDLMNAMAPTHSD17B10
	SCHEMBL17560229	0.76	NPSR1 (0.60)	NPSR1PRMT5ALDH1A1HPGDLMNA
	SCHEMBL25110080	0.76	HSD17B10 (0.67)	NPSR1PRMT5ALDH1A1HPGDLMNA
	SCHEMBL15651187	0.74	ALDH1A1 (0.48)	NPSR1ALDH1A1HPGDHTTHSD17B10
	SCHEMBL1520673	0.73	NPSR1 (1.00)	NPSR1ALDH1A1LMNAMAPTHTT
	SCHEMBL27858196	0.72	TSHR (0.48)	ALDH1A1HPGDLMNAMAPTHSD17B10
	SCHEMBL29057142	0.72	PDE4B (0.42)	PRMT5ALDH1A1HPGDHSD17B10
	SCHEMBL30339009	0.72	PDE4B (0.42)	PRMT5ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.