Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12788700 | 0.80 | POLB (0.50) | BIRC2POLBHRH4KMT2A | |
| SCHEMBL17560423 | 0.80 | BIRC2 (0.36) | BIRC2POLBHRH4CYP2C9EPHX1 | |
| SCHEMBL2952691 | 0.80 | HTT (0.57) | HTTMAPK1KDM4EALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL29943384 | 0.78 | HTT (0.55) | HTTMAPK1KDM4EALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL17560454 | 0.78 | HTT (0.55) | HTTMAPK1KDM4EALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL28848375 | 0.78 | HTT (0.55) | HTTMAPK1KDM4EALDH1A1POLB | |
| SCHEMBL13472167 | 0.76 | LMNA (0.47) | KDM4EBIRC2LMNAHRH4GAA | |
| SCHEMBL28120270 | 0.75 | BIRC2 (0.49) | BIRC2HRH4 | |
| SCHEMBL27957087 | 0.75 | BIRC2 (0.49) | BIRC2HRH4 | |
| SCHEMBL28048803 | 0.75 | BIRC2 (0.49) | BIRC2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016034134-A1 | HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-03-10 | — | — | WO | disclosed |