Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22322309 | 0.98 | ALDH1A1 (0.42) | ALDH1A1POLBHPGDSMN1; SMN2HSD11B1 | |
| SCHEMBL17560436 | 0.82 | CHRNB2 (0.42) | HPGDHSD11B1 | |
| SCHEMBL29999217 | 0.82 | ALDH1A1 (0.36) | ALDH1A1POLBHPGDSMN1; SMN2GAA | |
| SCHEMBL1423963 | 0.80 | ALDH1A1 (0.39) | ALDH1A1POLBHPGDSMN1; SMN2HSD11B1 | |
| SCHEMBL31689906 | 0.78 | ALDH1A1 (0.32) | ALDH1A1POLBSMN1; SMN2GAAMAPT | |
| SCHEMBL30443406 | 0.76 | ALDH1A1 (0.54) | ALDH1A1POLBHPGDSMN1; SMN2GAA | |
| SCHEMBL28195034 | 0.75 | ALDH1A1 (0.43) | ALDH1A1POLBHPGDSMN1; SMN2GAA | |
| SCHEMBL11456775 | 0.73 | ALDH1A1 (0.46) | ALDH1A1POLBHPGDSMN1; SMN2GAA | |
| SCHEMBL26110865 | 0.73 | ALDH1A1 (0.47) | ALDH1A1POLBHPGDSMN1; SMN2GAA | |
| SCHEMBL4469459 | 0.73 | ALDH1A1 (0.42) | ALDH1A1POLBHPGDSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4419527-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | Artios Pharma Limited (GB) | 2024-08-28 | — | — | EP | disclosed |
| WO-2023067355-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2023-04-27 | — | — | WO | disclosed |
| WO-2016034134-A1 | HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-03-10 | — | — | WO | disclosed |