Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 12/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85836 | 0.87 | THRB (0.50) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16309328 | 0.86 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16385235 | 0.86 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL2720550 | 0.86 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16384917 | 0.86 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL17225745 | 0.85 | TSHR (0.57) | TSHRTHRBACHE | |
| SCHEMBL4980959 | 0.84 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL29100295 | 0.84 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL29100282 | 0.84 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27776277 | 0.84 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1983017-B1 | CURABLE COMPOSITION CONTAINING THIOL COMPOUND | SHOWA DENKO KK (JP) | 2012-04-18 | — | — | EP | disclosed |