Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 13/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29100295 | 1.00 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16309328 | 0.95 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL25298348 | 0.94 | TSHR (0.73) | TSHRTHRBACHE | |
| SCHEMBL28459056 | 0.94 | TSHR (0.73) | TSHRTHRBACHE | |
| SCHEMBL16803336 | 0.93 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9421249 | 0.93 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4983337 | 0.92 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4977289 | 0.92 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16806093 | 0.91 | THRB (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4980959 | 0.90 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116924912-A | Molecule for improving hair toughness and application thereof | 江南大学 | 2023-10-24 | — | — | CN | claimed |
| CN-116924912-A | Molecule for improving hair toughness and application thereof | 江南大学 | 2023-10-24 | — | — | CN | disclosed |