Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FABP6 | P51161 | 1/20 | 0.42 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9127349 | 0.87 | GGPS1 (0.54) | LMNAPOLBMEN1KMT2AGGPS1 | |
| SCHEMBL7854588 | 0.85 | LMNA (0.69) | LMNAPOLBMEN1KMT2AKCNH2 | |
| SCHEMBL24462989 | 0.81 | GGPS1 (0.42) | LMNAPOLBMEN1KMT2AKCNH2 | |
| SCHEMBL22778950 | 0.81 | GGPS1 (0.46) | LMNAPOLBMEN1KMT2AGGPS1 | |
| SCHEMBL17694874 | 0.79 | GGPS1 (0.43) | LMNAPOLBMEN1KMT2AGGPS1 | |
| SCHEMBL26790579 | 0.78 | GGPS1 (0.43) | LMNAPOLBMEN1KMT2AGGPS1 | |
| SCHEMBL5084482 | 0.78 | AR (0.43) | LMNAPOLBMEN1KMT2AGGPS1 | |
| SCHEMBL17563257 | 0.77 | CHRNB2 (0.41) | LMNAPOLBMEN1KMT2ANPC1 | |
| SCHEMBL8876066 | 0.74 | AR (0.43) | LMNAPOLBMEN1KMT2AGGPS1 | |
| SCHEMBL26790580 | 0.74 | GGPS1 (0.37) | LMNAPOLBMEN1KMT2AGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822119-B2 | Inhibitors of lysine specific demethylase-1 | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-11-21 | — | — | US | disclosed |
| US-20160108046-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | CELGENE QUANTICEL RESEARCH, INC. | 2016-04-21 | — | — | US | disclosed |
| WO-2016037005-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108046-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | KDM1B, KDM1A, KDM3A | LMNA 2879/4885POLB 2723/4885MEN1 1844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.