Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | DNM2 | P50570 | 7/20 | 0.49 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937257 | 1.00 | KMT2A (0.77) | KMT2ALMNADNM2KCNH3NR1I2 | |
| SCHEMBL1562316 | 1.00 | KMT2A (0.77) | KMT2ALMNADNM2KCNH3NR1I2 | |
| SCHEMBL2238412 | 1.00 | KMT2A (0.77) | KMT2ALMNADNM2KCNH3NR1I2 | |
| SCHEMBL2328267 | 1.00 | KMT2A (0.77) | KMT2ALMNADNM2KCNH3NR1I2 | |
| SCHEMBL10912439 | 1.00 | KMT2A (0.77) | KMT2ALMNADNM2KCNH3NR1I2 | |
| SCHEMBL616128 | 0.98 | KMT2A (0.74) | KMT2ALMNADNM2KCNH3NR1I2 | |
| SCHEMBL7862893 | 0.96 | KMT2A (0.83) | KMT2ALMNADNM2KCNH3NR1I2 | |
| SCHEMBL11787843 | 0.96 | KMT2A (0.83) | KMT2ALMNADNM2KCNH3NR1I2 | |
| SCHEMBL20694824 | 0.94 | KMT2A (0.81) | KMT2ALMNADNM2KCNH3NR1I2 | |
| SCHEMBL7100653 | 0.94 | KMT2A (0.80) | KMT2ALMNADNM2KCNH3NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018175958-A1 | THIOREDOXIN MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-09-27 | — | — | WO | disclosed |
| WO-2016036847-A9 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2017-04-20 | — | — | WO | disclosed |
| US-20170088671-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2017-03-30 | — | — | US | disclosed |
| US-20170088671-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2017-03-30 | — | — | US | disclosed |
| US-9562137-B2 | Synthetic polymers and methods of making and using the same | BATTELLE MEMORIAL INSTITUTE (US) | 2017-02-07 | — | — | US | disclosed |
| US-9562137-B2 | Synthetic polymers and methods of making and using the same | BATTELLE MEMORIAL INSTITUTE (US) | 2017-02-07 | — | — | US | disclosed |
| US-20160257785-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | U.S. DEPARTMENT OF ENERGY | 2016-09-08 | — | — | US | disclosed |
| US-20160257785-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | U.S. DEPARTMENT OF ENERGY | 2016-09-08 | — | — | US | disclosed |
| US-9365676-B2 | Synthetic polymers and methods of making and using the same | BATTELLE MEMORIAL INSTITUTE (US) | 2016-06-14 | — | — | US | disclosed |
| US-9365676-B2 | Synthetic polymers and methods of making and using the same | BATTELLE MEMORIAL INSTITUTE (US) | 2016-06-14 | — | — | US | disclosed |
| US-20160068635-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE | 2016-03-10 | — | — | US | disclosed |
| US-20160068635-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE | 2016-03-10 | — | — | US | disclosed |
| WO-2016036847-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2016-03-10 | — | — | WO | disclosed |