SCHEMBL1562316

SCHEMBL1562316

CCCCCCNc1nc(Cl)nc(Cl)n1

nearest known ligand 0.77

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.77
LMNA P02545 1/20 0.52
DNM2 P50570 7/20 0.49
KCNH3 Q9ULD8 2/20 0.49
NR1I2 O75469 1/20 0.46
AHR P35869 1/20 0.46
SLC29A1 Q99808 1/20 0.42
PKM P14618 1/20 0.42
RAD52 P43351 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2328267 1.00 KMT2A (0.77) KMT2ALMNADNM2KCNH3NR1I2
SCHEMBL17563553 1.00 KMT2A (0.77) KMT2ALMNADNM2KCNH3NR1I2
SCHEMBL2238412 1.00 KMT2A (0.77) KMT2ALMNADNM2KCNH3NR1I2
SCHEMBL10912439 1.00 KMT2A (0.77) KMT2ALMNADNM2KCNH3NR1I2
SCHEMBL7937257 1.00 KMT2A (0.77) KMT2ALMNADNM2KCNH3NR1I2
SCHEMBL616128 0.98 KMT2A (0.74) KMT2ALMNADNM2KCNH3NR1I2
SCHEMBL7862893 0.96 KMT2A (0.83) KMT2ALMNADNM2KCNH3NR1I2
SCHEMBL11787843 0.96 KMT2A (0.83) KMT2ALMNADNM2KCNH3NR1I2
SCHEMBL20694824 0.94 KMT2A (0.81) KMT2ALMNADNM2KCNH3NR1I2
SCHEMBL7100653 0.94 KMT2A (0.80) KMT2ALMNADNM2KCNH3NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328076-B2 Molecular glasses with functionalizable groups HER MAJESTY IN THE RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF DEFENSE (CA) 2016-05-03 US claimed
WO-2023141089-A1 SHAPED ARTIFICIAL POLYMER ARTICLES WITH HYBRID METAL OXIDE PARTICLES BASF SE (DE) 2023-07-27 WO disclosed
WO-2023141091-A1 SHAPED ARTIFICIAL POLYMER ARTICLES WITH CLOSED-CELL METAL OXIDE PARTICLES BASF SE (DE) 2023-07-27 WO disclosed
US-9346768-B2 Molecular glasses with functionalizable groups HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENSE (CA) 2016-05-24 US disclosed
US-9328076-B2 Molecular glasses with functionalizable groups HER MAJESTY IN THE RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF DEFENSE (CA) 2016-05-03 US disclosed
US-20150232433-A1 Molecular Glasses With Functionalizable Groups HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENCE (CA) 2015-08-20 US disclosed
US-20140005370-A1 MOLECULAR GLASSES WITH FUNCTIONALIZABLE GROUPS HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENCE (CA) 2014-01-02 US disclosed
US-7999101-B2 Genetic material complexing and internalizing capacity; low cytotoxicity; such as 2-[4-(3-amino-propylamino)-6-tetradecylamino-[1,3,5]triazin-2-ylamino]-ethanethiol or its disulphide dimer POLITECNICO DI MILANO (IT) 2011-08-16 US disclosed
US-7999101-B2 Genetic material complexing and internalizing capacity; low cytotoxicity; such as 2-[4-(3-amino-propylamino)-6-tetradecylamino-[1,3,5]triazin-2-ylamino]-ethanethiol or its disulphide dimer POLITECNICO DI MILANO (IT) 2011-08-16 US disclosed
US-7999101-B2 Genetic material complexing and internalizing capacity; low cytotoxicity; such as 2-[4-(3-amino-propylamino)-6-tetradecylamino-[1,3,5]triazin-2-ylamino]-ethanethiol or its disulphide dimer POLITECNICO DI MILANO (IT) 2011-08-16 US disclosed
EP-1846378-B1 CATIONIC LIPIDS FOR THE TRANSFECTION OF NUCLEIC ACIDS MILANO POLITECNICO (IT) 2011-04-06 EP disclosed
US-20080146518-A1 Cationic Lipids for the Transfection of Nucleic Acids POLITECNICO DI MILANO (IL) 2008-06-19 US disclosed
US-20080146518-A1 Cationic Lipids for the Transfection of Nucleic Acids POLITECNICO DI MILANO (IL) 2008-06-19 US disclosed
US-20080146518-A1 Cationic Lipids for the Transfection of Nucleic Acids POLITECNICO DI MILANO (IL) 2008-06-19 US disclosed
EP-1846378-A2 CATIONIC LIPIDS FOR THE TRANSFECTION OF NUCLEIC ACIDS Politecnico Di Milano (IT) 2007-10-24 EP disclosed
WO-2006087752-A2 CATIONIC LIPIDS FOR THE TRANSFECTION OF NUCLEIC ACIDS POLITECNICO DI MILANO (IT) 2006-08-24 WO disclosed
US-4515716-A COLORFAST ORANGE TO BLUE SHADES MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1985-05-07 US disclosed
US-3931165-A INSECTICIDES, HERBICIDES BARER SOL J 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140005370-A1 MOLECULAR GLASSES WITH FUNCTIONALIZABLE GROUPS GNG2, GDI1, F12 KMT2A 3635/4885LMNA 3537/4885DNM2 2586/4885
US-20150232433-A1 Molecular Glasses With Functionalizable Groups GDI1, GNG2, F12 KMT2A 3732/4885LMNA 3433/4885DNM2 2625/4885
US-20080146518-A1 Cationic Lipids for the Transfection of Nucleic Acids AARS1, HARS1, LPAR3 KMT2A 826/4885LMNA 803/4885DNM2 1409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.