Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | DNM2 | P50570 | 7/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912439 | 0.98 | KMT2A (0.77) | KMT2ALMNAKCNH3NR1I2AHR | |
| SCHEMBL2238412 | 0.98 | KMT2A (0.77) | KMT2ALMNAKCNH3NR1I2AHR | |
| SCHEMBL2328267 | 0.98 | KMT2A (0.77) | KMT2ALMNAKCNH3NR1I2AHR | |
| SCHEMBL1562316 | 0.98 | KMT2A (0.77) | KMT2ALMNAKCNH3NR1I2AHR | |
| SCHEMBL17563553 | 0.98 | KMT2A (0.77) | KMT2ALMNAKCNH3NR1I2AHR | |
| SCHEMBL7937257 | 0.98 | KMT2A (0.77) | KMT2ALMNAKCNH3NR1I2AHR | |
| SCHEMBL7100653 | 0.96 | KMT2A (0.80) | KMT2ALMNAKCNH3NR1I2AHR | |
| SCHEMBL7862893 | 0.94 | KMT2A (0.83) | KMT2ALMNAKCNH3NR1I2AHR | |
| SCHEMBL11787843 | 0.94 | KMT2A (0.83) | KMT2ALMNAKCNH3NR1I2AHR | |
| SCHEMBL987508 | 0.94 | KMT2A (0.66) | KMT2ALMNAKCNH3NR1I2AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4683308-A | Process for the preparation of 2-arylamino-4,6-dichloro-s-triazines | BAYER AKTIENGESELLSCHAFT (DE) | 1987-07-28 | — | — | US | claimed |
| WO-2020146779-A1 | mTORC1 INHIBITORS FOR ACTIVATING AUTOPHAGY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-07-16 | — | — | WO | disclosed |
| WO-2018175958-A1 | THIOREDOXIN MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-09-27 | — | — | WO | disclosed |
| EP-2481730-B1 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | DOW AGROSCIENCES LLC (US) | 2013-12-18 | — | — | EP | disclosed |
| EP-2481731-B1 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | DOW AGROSCIENCES LLC (US) | 2013-10-23 | — | — | EP | disclosed |
| EP-2197857-B1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2013-03-06 | — | — | EP | disclosed |
| EP-2481731-A1 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | Dow AgroSciences LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| EP-2481730-A1 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | Dow AgroSciences LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| US-8188273-B2 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | DOW AGROSCIENCES, LLC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20120040837-A1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2012-02-16 | — | — | US | disclosed |
| US-4876253-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-24 | — | — | US | disclosed |
| EP-0334135-A2 | Trisubstituted 1,3,5-triazine-2,4,6-triones | BAYER AG (DE) | 1989-09-27 | — | — | EP | disclosed |
| US-4839359-A | POSTEMERGENCE HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-13 | — | — | US | disclosed |
| EP-0279122-A2 | Reactive dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-24 | — | — | EP | disclosed |
| EP-0248288-A2 | Trisubstituted 1,3,5-triazine-2,4,6-triones | BAYER AG (DE) | 1987-12-09 | — | — | EP | disclosed |
| US-4683308-A | Process for the preparation of 2-arylamino-4,6-dichloro-s-triazines | BAYER AKTIENGESELLSCHAFT (DE) | 1987-07-28 | — | — | US | disclosed |
| US-4683308-A | Process for the preparation of 2-arylamino-4,6-dichloro-s-triazines | BAYER AKTIENGESELLSCHAFT (DE) | 1987-07-28 | — | — | US | disclosed |
| US-4683308-A | Process for the preparation of 2-arylamino-4,6-dichloro-s-triazines | BAYER AKTIENGESELLSCHAFT (DE) | 1987-07-28 | — | — | US | disclosed |
| US-4116700-A | PARTIALLY HYDROLYZED BIS-(DICHLOROTRIAZIN-2-YL)-ALKYLAMINES OR -ARYLAMINES | AGFA-GEVAERT, A.G. (DE) | 1978-09-26 | — | — | US | disclosed |
| US-3939158-A | N-(2,4-dihalo-S-triazin-6-yl)-ureas and process for their manufacture | CIBA-GEIGY AG (CH) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040837-A1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | HELZ, API5, CRYZ | KMT2A 1091/4885LMNA 3505/4885KCNH3 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.