Propylene Oxide

Propylene Oxide

SCHEMBL1756464

C1CO1.CC1CO1.ClCC1CO1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.65
TDP1 Q9NUW8 1/20 0.65
CHRM2 P08172 6/20 0.39
CHRM5 P08912 6/20 0.39
CHRM3 P20309 5/20 0.39
CHRM4 P08173 4/20 0.39
CHRM1 P11229 3/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
KDM4E B2RXH2 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Oxide SCHEMBL2261389 0.92
Oxirane SCHEMBL397671 0.89
SCHEMBL118159 0.81
SCHEMBL17976 0.81
SCHEMBL3701513 0.81 ALDH1A1 (1.00) ALDH1A1TDP1TSHRMAPK1
SCHEMBL31018802 0.81
SCHEMBL117455 0.81
Propane SCHEMBL23011948 0.78
Methyl Alcohol SCHEMBL28760693 0.78
Propane SCHEMBL23011949 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2316884-B1 VULCANIZABLE RUBBER COMPOSITION FOR AIR SPRING, AND MOLDED RUBBER ARTICLE FOR AIR SPRING OSAKA SODA CO LTD (JP) 2018-01-24 EP disclosed
US-8530587-B2 Vulcanizable rubber composition for use in an air spring and rubber formed product for use in an air spring DAISO CO., LTD (JP) 2013-09-10 US disclosed
US-20110160342-A1 VULCANIZABLE RUBBER COMPOSITION FOR USE IN AN AIR SPRING AND RUBBER FORMED PRODUCT FOR USE IN AN AIR SPRING DAISO CO., LTD. (JP) 2011-06-30 US disclosed
EP-2316884-A1 VULCANIZABLE RUBBER COMPOSITION FOR AIR SPRING, AND MOLDED RUBBER ARTICLE FOR AIR SPRING DAISO CO., LTD. (JP) 2011-05-04 EP disclosed
US-5310818-A Vulcanizable chlorine-containing rubber compositions containing triazinethiol amine salt vulcanizing agents MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-05-10 US disclosed
EP-0292263-B1 VULCANIZABLE RUBBER COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-07-14 EP disclosed
US-5004787-A With aliphatic or aromatic carboxylic acid amine salts or phenolic amine salts as promoters in chlorinated rubbers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-04-02 US disclosed
EP-0292263-A2 Vulcanizable rubber composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-11-23 EP disclosed
US-4048261-A Vulcanizable compositions of a halogen-containing polymer and a diene-nitrile rubber having active halogen cure sites THE B. F. GOODRICH COMPANY (US) 1977-09-13 US disclosed
US-3968065-A Vulcanizable polymer blends of a halogen-containing polymer and a carboxyl-containing polymer THE B. F. GOODRICH COMPANY (US) 1976-07-06 US disclosed