SCHEMBL1756465

SCHEMBL1756465

CC(O)CC(=O)OC1=CC=CCC1=S

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1756477 1.00 ALOX15 (0.31) ALOX15
SCHEMBL1756470 0.85
SCHEMBL6942777 0.81 ESR1 (0.35) ALOX15
SCHEMBL1756473 0.80
SCHEMBL5676961 0.80
SCHEMBL7127288 0.78 MGAM (0.35)
SCHEMBL6278260 0.75 LMNA (0.31)
SCHEMBL18203168 0.75
SCHEMBL11002171 0.75 LMNA (0.40)
SCHEMBL10682653 0.74 LMNA (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1591531-B1 PROCESS FOR ACYL-TRANSFER ENZYME REACTIONS WITH ACYL- COENZYME A SHOWA DENKO KK (JP) 2016-03-23 EP claimed
US-7943351-B2 Method for acyltransferase reaction using acyl coenzyme A SHOWA DENKO K.K. (JP) 2011-05-17 US claimed
US-20090111153-A1 METHOD FOR ACYLTRANSFERASE REACTION USING ACYL COENZYME A SHOWA DENKO K.K. 2009-04-30 US claimed
US-7476521-B2 acyl group of acyl coenzyme A is transferred to an acyl group receptor characterized in that the reaction is carried out by production and/or reproduction of acyl coenzyme A from coenzyme A in a reaction system by a chemical thioester exchange reaction with acylthioester SHOWA DENKO K.K. (JP) 2009-01-13 US claimed
US-20060148048-A1 acyl group of acyl coenzyme A is transferred to an acyl group receptor characterized in that the reaction is carried out by production and/or reproduction of acyl coenzyme A from coenzyme A in a reaction system by a chemical thioester exchange reaction with acylthioester SHOWA DENKO K.K. (JP) 2006-07-06 US claimed
EP-1591531-A1 PROCESS FOR ACYL-TRANSFER ENZYME REACTIONS WITH ACYL- COENZYME A Showa Denko K.K. (JP) 2005-11-02 EP claimed
EP-1591531-B1 PROCESS FOR ACYL-TRANSFER ENZYME REACTIONS WITH ACYL- COENZYME A SHOWA DENKO KK (JP) 2016-03-23 EP disclosed
US-7943351-B2 Method for acyltransferase reaction using acyl coenzyme A SHOWA DENKO K.K. (JP) 2011-05-17 US disclosed
US-20090111153-A1 METHOD FOR ACYLTRANSFERASE REACTION USING ACYL COENZYME A SHOWA DENKO K.K. 2009-04-30 US disclosed
US-7476521-B2 acyl group of acyl coenzyme A is transferred to an acyl group receptor characterized in that the reaction is carried out by production and/or reproduction of acyl coenzyme A from coenzyme A in a reaction system by a chemical thioester exchange reaction with acylthioester SHOWA DENKO K.K. (JP) 2009-01-13 US disclosed
US-20060148048-A1 acyl group of acyl coenzyme A is transferred to an acyl group receptor characterized in that the reaction is carried out by production and/or reproduction of acyl coenzyme A from coenzyme A in a reaction system by a chemical thioester exchange reaction with acylthioester SHOWA DENKO K.K. (JP) 2006-07-06 US disclosed
EP-1591531-A1 PROCESS FOR ACYL-TRANSFER ENZYME REACTIONS WITH ACYL- COENZYME A Showa Denko K.K. (JP) 2005-11-02 EP disclosed