SCHEMBL17565197

SCHEMBL17565197

Cc1cc(C)c(OCCO)c(C(c2ccccc2)c2cc(C)cc(C)c2OCCO)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 2/20 0.40
SLC6A2 P23975 2/20 0.40
SLC6A4 P31645 2/20 0.40
SLC6A3 Q01959 2/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ATM Q13315 1/20 0.39
ALDH1A1 P00352 1/20 0.39
RECQL P46063 1/20 0.39
MAPT P10636 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
POLB P06746 1/20 0.37
SCN4A P35499 2/20 0.37
SCN8A Q9UQD0 1/20 0.36
LMNA P02545 1/20 0.36
HTR2A P28223 2/20 0.36
HTR7 P34969 2/20 0.36
ADRA1A P35348 1/20 0.36
HTR6 P50406 1/20 0.36
BRD4 O60885 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17565190 0.90 HTR1A (0.34) HTR1ASLC6A2SLC6A4SLC6A3MEN1
SCHEMBL17565200 0.87 HTR1A (0.33) HTR1ASLC6A2SLC6A4SLC6A3MEN1
SCHEMBL24411219 0.82 L3MBTL1 (0.38) ALDH1A1RECQLMAPTL3MBTL1SCN4A
SCHEMBL17565198 0.80 MAPT (0.40) HTR1AALDH1A1MAPTL3MBTL1POLB
SCHEMBL17565212 0.79 HTR1A (0.43) HTR1AMEN1KMT2AATMALDH1A1
SCHEMBL12113659 0.79 HTR1A (0.49) HTR1AMEN1KMT2AALDH1A1MAPT
SCHEMBL24411327 0.77 MRGPRX4 (0.41) ALDH1A1MAPTL3MBTL1
SCHEMBL17565210 0.76 HTR1A (0.47) HTR1AMEN1KMT2AALDH1A1MAPT
SCHEMBL3398525 0.76 HTR1A (0.58) HTR1AMEN1KMT2AATMALDH1A1
SCHEMBL17565196 0.75 HTR1A (0.34) HTR1AHTR2AHTR7ADRA1ABRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160071992-A1 BACK SHEET FOR SOLAR CELLS AND SOLAR CELL MODULE FUJIFILM CORPORATION (JP) 2016-03-10 US disclosed