Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | HPGDS | O60760 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13352112 | 0.91 | ALDH1A1 (0.60) | PKMPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL13352244 | 0.90 | MEN1 (0.71) | PKMPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL9607110 | 0.88 | ALDH1A1 (0.57) | PKMPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL26215467 | 0.87 | PKM (0.62) | PKMPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL29008942 | 0.85 | MEN1 (0.82) | PKMPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL30263637 | 0.85 | MEN1 (0.82) | PKMPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL15417362 | 0.85 | MEN1 (0.82) | PKMPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL30377355 | 0.85 | MEN1 (0.82) | PKMPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL17565743 | 0.85 | ALDH1A1 (0.47) | PKMPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL13352110 | 0.84 | PKM (0.64) | PKMPOLBALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3045170-A1 | HALOGENATED ANALOGUES OF ANTI-FIBROTIC AGENTS | Fibrotech Therapeutics PTY LTD (AU) | 2016-07-20 | — | — | EP | disclosed |
| EP-2220028-B1 | HALOGENATED ANALOGUES OF ANTI-FIBROTIC AGENTS | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2016-03-09 | — | — | EP | disclosed |