⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1757360 | 0.85 | — | — | |
| SCHEMBL1756788 | 0.83 | EPHX1 (0.45) | — | |
| Urea SCHEMBL27771104 | 0.83 | RAB9A (0.46) | — | |
| SCHEMBL29818646 | 0.81 | EPHX1 (0.48) | — | |
| SCHEMBL21724593 | 0.81 | EPHX1 (0.48) | — | |
| SCHEMBL3267106 | 0.81 | EPHX1 (0.48) | — | |
| SCHEMBL11670372 | 0.81 | EPHX1 (0.48) | — | |
| SCHEMBL9344941 | 0.81 | TP53 (0.38) | — | |
| SCHEMBL840550 | 0.79 | — | — | |
| SCHEMBL27797987 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014070-A2 | NOVEL IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATIONS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1993-07-22 | — | — | WO | claimed |
| CN-114786774-A | Novel compounds | 维科尔药物公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-107837809-B | Catalyst for preparing n-propanol by catalytic hydrogenation of dimethyl malonate and preparation method and application thereof | 上海华谊能源化工有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-203440060-U | Device for recycling hydrogen from tail gas produced by hydrogenization reaction | NANJING RONGXIN CHEMICAL IND CO LTD | 2014-02-19 | — | — | CN | disclosed |
| CN-102304019-B | Method for removing propyl propionate in process for preparing normal propyl alcohol by hydrogenating propionaldehyde | NANJING RONGXIN CHEMICAL CO LTD | 2013-09-11 | — | — | CN | disclosed |
| CN-202170312-U | Device for removing by-product ester in process of preparing alcohol through aldehyde hydrogenation | NANJING RONGXIN CHEMICAL CO LTD | 2012-03-21 | — | — | CN | disclosed |
| CN-102304019-A | Method for removing propyl propionate in process for preparing normal propyl alcohol by hydrogenating propionaldehyde | NANJING RONGXIN CHEMICAL CO LTD | 2012-01-04 | — | — | CN | disclosed |
| US-7973163-B2 | Fused quinoline derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LTD. (JP) | 2011-07-05 | — | — | US | disclosed |
| US-7943770-B2 | Fused quinoline derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-17 | — | — | US | disclosed |
| EP-1740584-B9 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2010-06-09 | — | — | EP | disclosed |
| US-20090258893-A1 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-15 | — | — | US | disclosed |
| US-7592453-B2 | Fused quinoline derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-22 | — | — | US | disclosed |
| EP-2080760-A1 | Fused quinoline derivative and use thereof | Takeda Pharmaceutical Company Limited (JP) | 2009-07-22 | — | — | EP | disclosed |
| EP-1740584-B1 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2008-12-03 | — | — | EP | disclosed |
| US-20080039452-A1 | Fused Quinoline Derivative and Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-14 | — | — | US | disclosed |
| CN-101121659-A | Technique for producing organic carbonic acid ester by urea alcoholysis method and fixed bed reactor | SHANXI COAL CHEM INST (CN) | 2008-02-13 | — | — | CN | disclosed |
| CN-1976932-A | Fused quinoline derivative and use thereof | TAKEDA PHARMACEUTICAL (JP) | 2007-06-06 | — | — | CN | disclosed |
| EP-1740584-A1 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105802-A1 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-11-10 | — | — | WO | disclosed |
| WO-1993014070-A2 | NOVEL IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATIONS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1993-07-22 | — | — | WO | disclosed |