SCHEMBL17570490

SCHEMBL17570490

Cc1ccc(Cc2ccc(N3C(=O)C4C5C(=O)N(C)C(=O)C5C4C3=O)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.51
TP53 P04637 1/20 0.49
ALDH1A1 P00352 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
HPGD P15428 1/20 0.47
HTT P42858 1/20 0.47
TRIP13 Q15645 1/20 0.45
MGLL Q99685 2/20 0.44
FAAH O00519 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
F2 P00734 1/20 0.44
ELANE P08246 1/20 0.44
CTSG P08311 1/20 0.44
CMA1 P23946 1/20 0.44
CTRC Q99895 1/20 0.44
CACNA1B Q00975 1/20 0.44
APBA1 Q02410 1/20 0.44
GAA P10253 1/20 0.43
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17570488 0.90 TP53 (0.57) RAB9ATP53ALDH1A1SMN1; SMN2HPGD
SCHEMBL13855426 0.86 TP53 (0.44) RAB9ATP53ALDH1A1SMN1; SMN2HPGD
SCHEMBL16405696 0.85 TP53 (0.53) RAB9ATP53ALDH1A1SMN1; SMN2HPGD
SCHEMBL12137895 0.83 TP53 (0.54) RAB9ATP53ALDH1A1SMN1; SMN2HPGD
SCHEMBL12799500 0.83 TP53 (0.54) RAB9ATP53ALDH1A1SMN1; SMN2HPGD
SCHEMBL12605364 0.82 TP53 (0.65) RAB9ATP53ALDH1A1SMN1; SMN2HPGD
SCHEMBL12539789 0.81 TP53 (0.49) RAB9ATP53ALDH1A1SMN1; SMN2HPGD
SCHEMBL13556588 0.80 SMN1; SMN2 (0.72) TP53ALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL13855427 0.77 TP53 (0.46) RAB9ATP53ALDH1A1SMN1; SMN2HPGD
SCHEMBL1960172 0.77 ALDH1A1 (0.42) TP53ALDH1A1SMN1; SMN2HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10018876-B2 Liquid crystal display and method of manufacture thereof SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-10 US disclosed
US-20160370626-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-12-22 US disclosed
US-20160313609-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURE THEREOF SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-27 US disclosed
US-20160070142-A1 PHOTOALIGNMENT AGENT, PHOTOALIGNMENT LAYER, LIQUID CRYSTAL DISPLAY DEVICE, AND METHOD OF MANUFACTURING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-03-10 US disclosed