SCHEMBL16405696

SCHEMBL16405696

Cc1ccc(-c2ccc(N3C(=O)C4C5C(=O)N(C)C(=O)C5C4C3=O)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.53
F2 P00734 1/20 0.48
ELANE P08246 1/20 0.48
CTSG P08311 1/20 0.48
CMA1 P23946 1/20 0.48
CTRC Q99895 1/20 0.48
CACNA1B Q00975 1/20 0.47
APBA1 Q02410 1/20 0.47
GAA P10253 2/20 0.47
MGLL Q99685 1/20 0.46
MAPT P10636 2/20 0.44
RAB9A P51151 2/20 0.44
LMNA P02545 2/20 0.43
TSHR P16473 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 1/20 0.41
ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17570488 0.94 TP53 (0.57) TP53F2ELANECTSGCMA1
SCHEMBL13855427 0.91 TP53 (0.46) TP53F2ELANECTSGCMA1
SCHEMBL13855431 0.90 TP53 (0.51) TP53F2ELANECTSGCMA1
SCHEMBL12799500 0.87 TP53 (0.54) TP53F2ELANECTSGCMA1
SCHEMBL12137895 0.87 TP53 (0.54) TP53F2ELANECTSGCMA1
SCHEMBL12605364 0.87 TP53 (0.65) TP53F2ELANECTSGCMA1
SCHEMBL17570490 0.85 RAB9A (0.51) TP53F2ELANECTSGCMA1
SCHEMBL12539789 0.85 TP53 (0.49) TP53F2ELANECTSGCMA1
SCHEMBL13855428 0.82 LMNA (0.46) TP53F2ELANECTSGCMA1
SCHEMBL13855426 0.82 TP53 (0.44) TP53CACNA1BAPBA1GAAMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9353222-B2 Composition, polymer film, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-05-31 US disclosed
US-20150025200-A1 COMPOSITION, POLYMER FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150025200-A1 COMPOSITION, POLYMER FILM, AND DISPLAY DEVICE DDT, DTD1, DRD1 TP53 3397/4885F2 143/4885ELANE 2026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.