SCHEMBL1757341

SCHEMBL1757341

CCCNC(CC)N(C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.32
CARM1 Q86X55 1/20 0.32
PRMT6 Q96LA8 1/20 0.32
PRMT1 Q99873 1/20 0.32
PRMT8 Q9NR22 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169825 0.83 EPHX1 (0.42)
SCHEMBL2196022 0.82 PRMT3 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL28318346 0.81 EPHX1 (0.46)
SCHEMBL22631540 0.81 EPHX1 (0.46)
SCHEMBL28459714 0.81 EPHX1 (0.46)
SCHEMBL8410933 0.81 EPHX1 (0.46)
SCHEMBL19894618 0.81 EPHX1 (0.46)
SCHEMBL2129584 0.81 EPHX1 (0.46)
SCHEMBL27443494 0.81 EPHX1 (0.46)
SCHEMBL2207256 0.80 CYP2C9 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113877630-B Catalyst for preparing bis [ (3-dimethylamino) propyl ] amine and application thereof 万华化学集团股份有限公司 2022-11-08 CN disclosed
EP-1885718-B1 FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE LIFE TECHNOLOGIES CORP (US) 2017-03-15 EP disclosed
US-9366676-B2 Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use Life Technologies Corporation (US) 2016-06-14 US disclosed
US-9346919-B2 Polysiloxane-polyether copolymers with amino groups and/or quaternary ammonium groups in the polyether moiety and processes for the preparation thereof EVONIK DEGUSSA GMBH (DE) 2016-05-24 US disclosed
US-20150316558-A1 Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use MOLECULAR PROBES, INC. 2015-11-05 US disclosed
US-9115397-B2 Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use Life Technologies Corporation (US) 2015-08-25 US disclosed
US-20150004597-A1 Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use LIFE TECHNOLOGIES CORP (US) 2015-01-01 US disclosed
US-8865904-B2 Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use Life Technologies Corporation (US) 2014-10-21 US disclosed
US-20140303065-A1 Polysiloxane-polyether copolymers with amino groups and/or quaternary ammonium groups in the polyether moiety and processes for the preparation thereof EVONIK INDUSTRIES AG (DE) 2014-10-09 US disclosed
US-20130224735-A1 Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use Life Technologies Corporation (US) 2013-08-29 US disclosed
US-20120288855-A1 Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use Life Technologies Corporation (US) 2012-11-15 US disclosed
US-20110217699-A1 Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use Life Technologies Corporation (US) 2011-09-08 US disclosed
US-7943777-B2 Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use Life Technologies Corporation (US) 2011-05-17 US disclosed
US-20100143917-A1 FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE Life Technologies Corporation (US) 2010-06-10 US disclosed
US-7598390-B2 Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use Life Technologies Corporation (US) 2009-10-06 US disclosed
EP-1885718-A1 FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE Molecular Probes, Inc. (US) 2008-02-13 EP disclosed
WO-2006124816-A1 FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE MOLECULAR PROBES, INC. (US) 2006-11-23 WO disclosed
US-20060263844-A1 Flourescent chemical compounds having high selectivity for double standard DNA, and methods for their use MOLECULAR PROBES, INC. 2006-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110217699-A1 Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use POLRMT, DNA2, NSUN2 PRMT3 2950/4885CARM1 1909/4885PRMT6 2945/4885
US-20120288855-A1 Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use POLRMT, DNA2, NSUN2 PRMT3 2950/4885CARM1 1909/4885PRMT6 2945/4885
US-20100143917-A1 FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE POLRMT, DNA2, NSUN2 PRMT3 2950/4885CARM1 1909/4885PRMT6 2945/4885
US-20150316558-A1 Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use POLRMT, DNA2, NSUN2 PRMT3 2950/4885CARM1 1909/4885PRMT6 2945/4885
US-20150004597-A1 Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use POLRMT, DNA2, NSUN2 PRMT3 2950/4885CARM1 1909/4885PRMT6 2945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.