Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 5/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17577137 | 0.89 | THRB (0.36) | TSHRALDH1A1CYP3A4THRBRARB | |
| SCHEMBL17577132 | 0.88 | THRB (0.44) | TSHRALDH1A1THRBRARBHPGD | |
| SCHEMBL17577140 | 0.88 | THRB (0.44) | TSHRALDH1A1THRBRARBHPGD | |
| SCHEMBL17577193 | 0.88 | TSHR (0.42) | TSHRALDH1A1CYP3A4THRBRARB | |
| SCHEMBL14028722 | 0.87 | TSHR (0.54) | TSHRALDH1A1CYP3A4THRBRARB | |
| SCHEMBL17578321 | 0.85 | THRB (0.40) | TSHRALDH1A1CYP3A4THRBRARB | |
| SCHEMBL17577139 | 0.85 | THRB (0.33) | TSHRALDH1A1CYP3A4THRB | |
| SCHEMBL17577123 | 0.84 | THRB (0.35) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL19730216 | 0.82 | ALDH1A1 (0.46) | TSHRALDH1A1CYP3A4THRBAKR1B10 | |
| SCHEMBL19730228 | 0.82 | ALDH1A1 (0.46) | TSHRALDH1A1CYP3A4THRBAKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9594318-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2017-03-14 | — | — | US | disclosed |
| US-20160070184-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-03-10 | — | — | US | disclosed |