SCHEMBL17577166

SCHEMBL17577166

C=CC(=O)OCCCCCc1ccc(-c2cc(CC(F)(F)F)c3ccc4cc(C(C)(C)C)cc5ccc2c3c45)cc1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
RARB P10826 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17577126 0.88 RARB (0.36) THRBALDH1A1CYP3A4TSHRRARB
SCHEMBL17577137 0.87 THRB (0.36) THRBALDH1A1CYP3A4TSHRRARB
SCHEMBL17577164 0.86 THRB (0.35) THRBALDH1A1CYP3A4TSHRRARB
SCHEMBL17577163 0.86 THRB (0.35) THRBALDH1A1CYP3A4TSHRRARB
SCHEMBL17578281 0.85 THRB (0.35) THRBALDH1A1CYP3A4TSHRRARB
SCHEMBL17577123 0.84 THRB (0.35) THRBALDH1A1CYP3A4TSHR
SCHEMBL17578277 0.83 MET (0.35) THRBTSHR
SCHEMBL17577160 0.82 THRB (0.42) THRBALDH1A1CYP3A4TSHRRARB
SCHEMBL19261022 0.77 THRB (0.32) THRBALDH1A1CYP3A4TSHR
SCHEMBL17577199 0.77 TSHR (0.32) THRBALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9594318-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-03-14 US disclosed
US-9594318-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-03-14 US disclosed
US-20160070184-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-03-10 US disclosed
US-20160070184-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-03-10 US disclosed