Biotin

Biotin

SCHEMBL1757916

NCCc1ccc(O)cc1.O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 5/20 0.69
▸ MEN1 O00255 1/20 0.69
▸ ABL1 P00519 1/20 0.69
▸ LMNA P02545 1/20 0.69
▸ PKM P14618 1/20 0.69
▸ IDE P14735 1/20 0.69
▸ MAPK1 P28482 1/20 0.69
▸ KMT2A Q03164 1/20 0.69
▸ RIN1 Q13671 1/20 0.69
▸ L3MBTL1 Q9Y468 1/20 0.69
▸ CA12 O43570 12/20 0.56
▸ CA1 P00915 12/20 0.56
▸ CA2 P00918 12/20 0.56
▸ CA9 Q16790 12/20 0.56
▸ HLCS P50747 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL7749208 1.00 TDP1 (0.69) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL3142794 0.93 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL23124079 0.86 TDP1 (0.81) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL453833 0.86 TDP1 (0.90) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL10618578 0.85 TDP1 (0.65) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL446893 0.85 TDP1 (0.79) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL2057282 0.85 TDP1 (0.87) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL6865574 0.85 TDP1 (0.87) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL5960334 0.84 TDP1 (0.85) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL739967 0.84 TDP1 (0.85) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591983-B Protein proximity marking method based on DNA nanotechnology and application thereof 中山大学 2023-07-21 — — CN claimed
CN-113899895-A Detection substrate based on macromolecule passivation self-polymerization type thin film coating modification and matched detection method and equipment 华中农业大学 2022-01-07 — — CN claimed
WO-2008128352-A1 METHODS AND COMPOSITIONS FOR SIGNAL AMPLIFICATION AXELA, INC. (CA) 2008-10-30 — — WO claimed
US-5731158-A ENZYME AMPLIFICATION OF DETECTOR SIGNAL E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-03-24 — — US claimed
US-5583001-A REACTING WITH A CONJUGATE CONSISTING OF A DETECTABLY LABELED SUBSTRATE SPECIFIC FOR ENZYME SYSTEM; DEPOSITS WHEREVER RECEPTOR IS IMMOBILIZED E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-12-10 — — US claimed
EP-0465577-B1 CATALYZED REPORTER DEPOSITION DU PONT (US) 1994-03-16 — — EP claimed
EP-0465577-A1 CATALYZED REPORTER DEPOSITION. DU PONT (US) 1992-01-15 — — EP claimed
WO-1990011523-A2 CATALYZED REPORTER DEPOSITION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-04 — — WO claimed
EP-4363613-A1 DETECTING METHYLCYTOSINE USING A MODIFIED BASE OPPOSITE TO THE METHYLCYTOSINE ILLUMINA, INC. (US) 2024-05-08 — — EP disclosed
CN-117561339-A Detection of methylcytosine using modified bases opposite methylcytosine 因美纳有限公司 2024-02-13 — — CN disclosed
WO-2023278744-A1 DETECTING METHYLCYTOSINE USING A MODIFIED BASE OPPOSITE TO THE METHYLCYTOSINE ILLUMINA, INC. (US) 2023-01-05 — — WO disclosed
CN-114729359-A Programmed DNA driven self-assembling RNA hydrogels 蛋白科技先锋公司 2022-07-08 — — CN disclosed
CN-113899895-A Detection substrate based on macromolecule passivation self-polymerization type thin film coating modification and matched detection method and equipment 华中农业大学 2022-01-07 — — CN disclosed
CN-113195731-A Sensitive glucose assay 豪夫迈·罗氏有限公司 2021-07-30 — — CN disclosed
WO-1998001757-A1 LABELLING AND SELECTION OF MOLECULES CAMBRIDGE ANTIBODY TECHNOLOGY LIMITED (GB) 1998-01-15 — — WO disclosed
US-5583001-A REACTING WITH A CONJUGATE CONSISTING OF A DETECTABLY LABELED SUBSTRATE SPECIFIC FOR ENZYME SYSTEM; DEPOSITS WHEREVER RECEPTOR IS IMMOBILIZED E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-12-10 — — US disclosed
EP-0465577-B1 CATALYZED REPORTER DEPOSITION DU PONT (US) 1994-03-16 — — EP disclosed
US-5196306-A Amplification E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-23 — — US disclosed
EP-0465577-A1 CATALYZED REPORTER DEPOSITION. DU PONT (US) 1992-01-15 — — EP disclosed
WO-1990011523-A2 CATALYZED REPORTER DEPOSITION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-04 — — WO disclosed
Send feedback