Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 16/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HK1 | P19367 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758023 | 0.91 | PTGDR2 (0.49) | ALDH1A1MAPTHSD17B10PTGDR2PTGS1 | |
| SCHEMBL1757520 | 0.90 | ALDH1A1 (0.52) | ALDH1A1MAPTHSD17B10PTGDR2LMNA | |
| SCHEMBL1757847 | 0.88 | ALDH1A1 (0.50) | ALDH1A1MAPTHSD17B10PTGDR2PTGS1 | |
| SCHEMBL1757691 | 0.87 | PTGDR2 (0.47) | ALDH1A1HSD17B10PTGDR2LMNAHPGD | |
| SCHEMBL1757624 | 0.82 | PTGDR2 (0.51) | ALDH1A1MAPTHSD17B10PTGDR2PTGS1 | |
| SCHEMBL1757393 | 0.81 | PTGDR2 (0.51) | ALDH1A1MAPTHSD17B10PTGDR2LMNA | |
| SCHEMBL2206663 | 0.80 | PTGDR2 (0.47) | PTGDR2PTGS1 | |
| SCHEMBL1757818 | 0.80 | PTGDR2 (0.63) | ALDH1A1MAPTPTGDR2CYP2C9CYP2C19 | |
| SCHEMBL1757905 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPTHSD17B10PTGDR2CYP2C9 | |
| SCHEMBL1757923 | 0.76 | PTGDR2 (0.82) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011055270-A1 | INDOLE BASED RECEPTOR CRTH2 ANTAGONISTS | WYETH LLC (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20110105509-A1 | INDOLE BASED RECEPTOR CRTH2 ANTAGONISTS | WYETH, LLC (US) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105509-A1 | INDOLE BASED RECEPTOR CRTH2 ANTAGONISTS | HRH2, CRHR2, CRHR1 | ALDH1A1 1069/4885MAPT 4275/4885HSD17B10 1166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.