Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10288032 | 0.87 | IRAK4 (0.44) | P2RX3HTR2AHTR2CDRD2DRD3 | |
| SCHEMBL15508018 | 0.84 | KMT2A (0.39) | TSHRHTTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7530694 | 0.81 | HTT (0.50) | LPAR1HPGDKDM4ETSHRHTT | |
| SCHEMBL17580433 | 0.79 | HTT (0.47) | LPAR1HPGDHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL12165535 | 0.78 | IRAK4 (0.45) | KDM4ECYP2C19SMN1; SMN2ALDH1A1IRAK4 | |
| SCHEMBL22158983 | 0.76 | RORC (0.56) | P2RX3LPAR1RORCHPGDKDM4E | |
| SCHEMBL543548 | 0.76 | TSHR (0.56) | KDM4ECYP2C9CYP2C19TSHRHTT | |
| SCHEMBL25659179 | 0.75 | MAOB (0.46) | P2RX3RORCHPGDKDM4ECYP2C9 | |
| SCHEMBL23190912 | 0.75 | CA12 (0.48) | HTTTOP2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL15283283 | 0.72 | EGFR (0.42) | HTR2AHTR2CDRD2DRD3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834248-B1 | NOVEL THIENOPYRIMIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | SANOFI SA (FR) | 2016-03-16 | — | — | EP | disclosed |