Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 5/20 | 0.44 |
| ▸ | PDE4A | P27815 | 4/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3515220 | 0.83 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4DCNR2 | |
| SCHEMBL3405276 | 0.82 | CNR2 (0.43) | CNR2ALOX5 | |
| SCHEMBL18138370 | 0.76 | SOAT1 (0.36) | PDE4BPDE4APDE4CPDE4DCNR2 | |
| SCHEMBL28112117 | 0.76 | THRA (0.37) | CNR2SOAT1PTPN1MAPT | |
| SCHEMBL27530678 | 0.73 | SOAT1 (0.40) | PDE4BPDE4APDE4CPDE4DCNR2 | |
| Anisole SCHEMBL29041606 | 0.73 | TRPV1 (0.36) | PDE4DCNR2KDM4EMAPT | |
| SCHEMBL28139838 | 0.72 | CNR2 (0.49) | PDE4BPDE4APDE4CPDE4DCNR2 | |
| SCHEMBL4937199 | 0.71 | KDM4E (0.40) | KDM4EMAPT | |
| Anisole SCHEMBL27966148 | 0.70 | MAPT (0.39) | MAPT | |
| Guaiacol SCHEMBL268884 | 0.70 | CNR1 (0.40) | CNR2MAPTALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257266-B1 | COMPOSITIONS DESIGNED TO PREVENT/PROTECT AGAINST PHOTOALLERGIC AND PHOTOTOXIC SKIN REACTIONS | BRAGUTI LODOVICO GIANLUCA (IT) | 2016-03-16 | — | — | EP | disclosed |