SCHEMBL3515220

SCHEMBL3515220

CCCCCCOc1c(O)c(OC)c(-c2ccccc2)c(CC)c1CC

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 5/20 0.48
PDE4A P27815 4/20 0.48
PDE4C Q08493 4/20 0.48
PDE4D Q08499 4/20 0.48
CNR2 P34972 1/20 0.41
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
SOAT1 P35610 1/20 0.37
GCGR P47871 1/20 0.37
NR5A1 Q13285 1/20 0.37
ALOX5 P09917 4/20 0.36
USP7 Q93009 2/20 0.36
LTA4H P09960 1/20 0.36
PTPN1 P18031 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17580697 0.83 PDE4B (0.44) PDE4BPDE4APDE4CPDE4DCNR2
SCHEMBL27530678 0.80 SOAT1 (0.40) PDE4BPDE4APDE4CPDE4DCNR2
SCHEMBL28139838 0.79 CNR2 (0.49) PDE4BPDE4APDE4CPDE4DCNR2
SCHEMBL18138370 0.77 SOAT1 (0.36) PDE4BPDE4APDE4CPDE4DCNR2
SCHEMBL9788120 0.76 GCGR (0.46) CNR2KDM4EMAPTSOAT1GCGR
SCHEMBL5590089 0.73 NR5A1 (0.44) NR5A1ALOX5LTA4H
SCHEMBL5587773 0.73 NR5A1 (0.44) NR5A1ALOX5LTA4H
SCHEMBL5588266 0.73 NR5A1 (0.44) NR5A1ALOX5LTA4H
SCHEMBL5588674 0.73 NR5A1 (0.44) NR5A1ALOX5LTA4H
SCHEMBL5589121 0.73 NR5A1 (0.44) NR5A1ALOX5LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8765688-B2 Anti-dandruff compositions containing peptides BASF SE (DE) 2014-07-01 US disclosed
US-20100310644-A1 ANTI-DANDRUFF COMPOSITIONS CONTAINING PEPTIDES BASF ,Trademarks and Licenses (DE) 2010-12-09 US disclosed
US-20080193405-A1 Use of a Water-In-Water Emulsion Polymers in the Form of a Thickener for Cosmetic Preparations BASF AKTIENGESELLSCHAFT (DE) 2008-08-14 US disclosed
US-20050189377-A1 Dispenser and cosmetic or dermatological preparation comprising an auxiliary for use with dispenser BEIERSDORF AG 2005-09-01 US disclosed
US-20050169855-A1 Cosmetic and dermatological light protection formulations BEIERSDORF AG 2005-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080193405-A1 Use of a Water-In-Water Emulsion Polymers in the Form of a Thickener for Cosmetic Preparations POLH, POLR1C, POLQ PDE4B 4630/4885PDE4A 4492/4885PDE4C 4341/4885
US-20050169855-A1 Cosmetic and dermatological light protection formulations USP30, CD63, TYR PDE4B 4713/4885PDE4A 4685/4885PDE4C 4780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.