Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | HTR6 | P50406 | 4/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 11/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17580734 | 0.90 | HTR2A (0.46) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL17580611 | 0.89 | HTR2A (0.48) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL3650493 | 0.88 | HTR2A (0.49) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL17580908 | 0.86 | HTR6 (0.57) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL17580826 | 0.86 | HTR2A (0.52) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL3651354 | 0.84 | HTR2A (0.49) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL3740556 | 0.82 | HTR2A (0.51) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL17580928 | 0.81 | HTR2A (0.50) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL17580842 | 0.81 | HTR6 (0.53) | HTR2AHTR6HTR1ADRD2HTR7 | |
| SCHEMBL3651344 | 0.80 | HTR2A (0.54) | HTR2AHTR6HTR1ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185555-B1 | QUINOLINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR | ABBVIE DEUTSCHLAND (DE) | 2016-03-16 | — | — | EP | claimed |