SCHEMBL1758266

SCHEMBL1758266

C1CC1OCC1CO1.COC([SiH3])OC

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 4/20 0.35
TDP1 Q9NUW8 1/20 0.34
MAPK1 P28482 1/20 0.33
PKM P14618 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL733109 0.82 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL16492070 0.80 TSHR (0.35) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28385789 0.80
SCHEMBL2114725 0.77 SMN1; SMN2 (0.42) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL9565285 0.76 TSHR (0.41) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL14415206 0.76 TSHR (0.44) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL14062955 0.76 TSHR (0.44) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL24046936 0.76 TSHR (0.42) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL805166 0.76 TSHR (0.38) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL24452968 0.76 TSHR (0.38) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8183584-B2 High efficient phosphor-converted light emitting diode EPISTAR CORPORATION (TW) 2012-05-22 US disclosed
US-7943948-B2 High efficient phosphor-converted light emitting diode EPISTAR CORPORATION (TW) 2011-05-17 US disclosed
US-20100200873-A1 HIGH EFFICIENT PHOSPHOR-CONVERTED LIGHT EMITTING DIODE EPISTAR CORPORATION (TW) 2010-08-12 US disclosed
US-7732827-B2 High efficient phosphor-converted light emitting diode EPISTAR CORPORATION (TW) 2010-06-08 US disclosed
US-20080006815-A1 High efficient phosphor-converted light emitting diode EPISTAR CORPORATION (TW) 2008-01-10 US disclosed