SCHEMBL2114725

SCHEMBL2114725

C1CC1OCC1CO1.CO[SiH](OC)OC

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 6/20 0.40
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 2/20 0.39
MAPK1 P28482 1/20 0.35
PKM P14618 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL733109 0.85 TSHR (0.50) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL9565285 0.79 TSHR (0.41) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL14415206 0.79 TSHR (0.44) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL27524327 0.79 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL14062955 0.79 TSHR (0.44) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL284231 0.79 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL17090758 0.79 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL24452968 0.78 TSHR (0.38) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
Methane SCHEMBL11467272 0.78 TSHR (0.40) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL1758266 0.77 TSHR (0.36) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112877010-A Natural rubber and metal hot vulcanization adhesive as well as preparation method and application thereof 中北大学 2021-06-01 CN claimed
EP-0136257-B1 SPHERICAL AMORPHOUS QUARTZ AND ITS USE IN FILLERS AND RESIN COMPOSITIONS CIBA-GEIGY AG (CH) 1988-01-20 EP claimed
CN-115820166-A Adhesive for bonding polyphosphazene rubber and metal, preparation method and application 西安近代化学研究所 2023-03-21 CN disclosed
CN-115039029-A Negative photosensitive resin composition and method for producing cured relief pattern 旭化成株式会社 2022-09-09 CN disclosed
CN-111448275-B Adhesive laminate, method for producing object with resin film, and method for producing cured sealing body with cured resin film 琳得科株式会社 2022-04-22 CN disclosed
CN-113345624-A Insulating coated conductive particle, anisotropic conductive adhesive, and connection structure 昭和电工材料株式会社 2021-09-03 CN disclosed
CN-113227234-A Resin composition for forming resist pattern and method for manufacturing semiconductor article 株式会社钟化 2021-08-06 CN disclosed
CN-109219637-B Sealing composition and semiconductor device 昭和电工材料株式会社 2021-05-25 CN disclosed
CN-111601849-A Sealing composition, method for producing same, and semiconductor device 日立化成株式会社 2020-08-28 CN disclosed
CN-111566163-A Sealing composition and semiconductor device 日立化成株式会社 2020-08-21 CN disclosed
CN-111566162-A Sealing composition and semiconductor device 日立化成株式会社 2020-08-21 CN disclosed
US-8159635-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-17 US disclosed
US-8044126-B2 Polyarylene sulfide resin composition, production method thereof and surface mount electronic component DIC CORPORATION (JP) 2011-10-25 US disclosed
US-20100328584-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2010-12-30 US disclosed
US-20100331463-A1 POLYARYLENE SULFIDE RESIN COMPOSITION, PRODUCTION METHOD THEREOF AND SURFACE MOUNT ELECTRONIC COMPONENT DIC CORPORATION (JP) 2010-12-30 US disclosed
EP-2236560-A1 POLY(ARYLENE SULFIDE) RESIN COMPOSITION, PROCESS FOR PRODUCTION THEREOF, AND SURFACE MOUNT ELECTRONIC COMPONENT DIC Corporation (JP) 2010-10-06 EP disclosed
US-20050089694-A1 Silane coated substrate MOFFATT WILLIAM A (US) 2005-04-28 US disclosed
US-20050089695-A1 Silane coated substrate MOFFAT WILLIAM A (US) 2005-04-28 US disclosed
CN-1392890-A Curable composition and use thereof MITSUI CHEMICALS INC (JP) 2003-01-22 CN disclosed
EP-0136257-B1 SPHERICAL AMORPHOUS QUARTZ AND ITS USE IN FILLERS AND RESIN COMPOSITIONS CIBA-GEIGY AG (CH) 1988-01-20 EP disclosed