Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26938153 | 1.00 | TSHR (0.38) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL15683200 | 0.95 | SMN1; SMN2 (0.38) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL13707142 | 0.89 | MEN1 (0.37) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9066827 | 0.89 | HCRTR2 (0.39) | TSHRSMN1; SMN2ALDH1A1TDP1HCRTR2 | |
| SCHEMBL7083176 | 0.84 | TSHR (0.40) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL733109 | 0.83 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL9066859 | 0.81 | SMN1; SMN2 (0.39) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL9918909 | 0.81 | SMN1; SMN2 (0.33) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL28385789 | 0.81 | — | — | |
| SCHEMBL24046936 | 0.81 | TSHR (0.42) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070594-A1 | HYDROGENATED BISPHENOL-A-BASED POLYMERS AS SUBSTITUTES FOR BISPHENOL-A-BASED POLYMERS | EMPIRE TECHNOLOGY DEVELOPMENT LLC | 2012-03-22 | — | — | US | disclosed |