SCHEMBL1758474

SCHEMBL1758474

FC(F)C(F)(F)C(F)(F)C(F)(F)COCC(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
HPGD P15428 1/20 0.40
XBP1 P17861 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP1A2 P05177 2/20 0.37
CYP2C19 P33261 2/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
TP53 P04637 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
TSHR P16473 2/20 0.34
USP2 O75604 1/20 0.34
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2C9 P11712 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL497555 0.93 LMNA (0.43) LMNANPSR1HPGDXBP1SMN1; SMN2
Hydrochloric Acid SCHEMBL31364520 0.91 LMNA (0.42) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL8731793 0.87 CYP1A2 (0.35) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL7151811 0.86 HTT (0.30) HTT
SCHEMBL1758932 0.84 NPSR1 (0.39) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL3418029 0.84 MAPT (0.45) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL11511024 0.84 MAPT (0.45) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL7156399 0.82 LMNA (0.43) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL9928685 0.82 LMNA (0.40) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL29048915 0.81 TSHR (0.41) LMNANPSR1HPGDXBP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2349967-B1 METHODS OF MAKING FLUORINATED ETHERS, FLUORINATED ETHERS, AND USES THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2016-03-23 EP disclosed
CN-102597156-B Method of using hydrofluoroethers as heat transfer fluids 3M INNOVATIVE PROPERTIES CO 2014-09-24 CN disclosed
US-8350094-B2 Methods of making fluorinated ethers, fluorinated ethers, and uses thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-01-08 US disclosed
US-8261560-B2 Methods of using hydrofluoroethers as heat transfer fluids 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-09-11 US disclosed
US-20110257073-A1 METHODS OF MAKING FLUORINATED ETHERS, FLUORINATED ETHERS, AND USES THEREOF 3M INNOVATIVE PROPERTIES COMPANY 2011-10-20 US disclosed
US-7988877-B2 Methods of making fluorinated ethers, fluorinated ethers, and uses thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-08-02 US disclosed
US-20110100601-A1 METHODS OF USING HYDROFLUOROETHERS AS HEAT TRANSFER FLUIDS 3M INNOVATIVE PROPERTIES COMPANY 2011-05-05 US disclosed
US-20100108934-A1 METHODS OF MAKING FLUORINATED ETHERS, FLUORINATED ETHERS, AND USES THEREOF 3M INNOVATIVE PROPERTIES COMPANY 2010-05-06 US disclosed
EP-0757399-B1 Non-aqueous electrolyte and lithium secondary battery SUMITOMO CHEMICAL CO (JP) 2003-04-02 EP disclosed
US-5795677-A Non-aqueous electrolyte and lithium secondary battery SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-08-18 US disclosed
EP-0757399-A1 Non-aqueous electrolyte and lithium secondary battery SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-02-05 EP disclosed