SCHEMBL9928685

SCHEMBL9928685

FC(F)C(F)(F)C(F)(F)C(F)(F)COCOCOCC(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
HPGD P15428 1/20 0.40
XBP1 P17861 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP1A2 P05177 2/20 0.37
CYP2C19 P33261 2/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
TP53 P04637 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
TSHR P16473 2/20 0.34
USP2 O75604 1/20 0.34
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2C9 P11712 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL497555 0.88 LMNA (0.43) LMNANPSR1HPGDXBP1SMN1; SMN2
Hydrochloric Acid SCHEMBL31364520 0.86 LMNA (0.42) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL7156399 0.82 LMNA (0.43) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL1758474 0.82 LMNA (0.40) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL1758932 0.80 NPSR1 (0.39) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL7155245 0.80 CYP1A2 (0.40) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL11511024 0.79 MAPT (0.45) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL3418029 0.79 MAPT (0.45) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL21906309 0.77 CYP1A2 (0.37) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL6466894 0.77 LMNA (0.38) LMNANPSR1HPGDXBP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2459759-B1 METHOD FOR SELECTIVELY RECOVERING AMERICIUM FROM AN AQUEOUS NITRIC PHASE COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2014-12-10 EP disclosed
US-8795610-B2 Process for reprocessing spent nuclear fuel not requiring a plutonium-reducing stripping operation COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2014-08-05 US disclosed
EP-2577676-B1 PROCESS FOR TREATING SPENT NUCLEAR FUEL WITHOUT REDUCTIVE DEEXTRACTION OF PLUTONIUM COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2014-07-23 EP disclosed
US-8753420-B2 Method for selectively recovering americium from a nitric aqueous phase COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2014-06-17 US disclosed
US-20130202501-A1 PROCESS FOR REPROCESSING SPENT NUCLEAR FUEL NOT REQUIRING A PLUTONIUM-REDUCING STRIPPING OPERATION COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2013-08-08 US disclosed
US-20120152059-A1 METHOD FOR SELECTIVELY RECOVERING AMERICIUM FROM A NITRIC AQUEOUS PHASE AREVA INC (FR) 2012-06-21 US disclosed