Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 9/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 2/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444746 | 0.86 | PDGFRB (0.58) | PDGFRBPDGFRAALDH1A1F2GLA | |
| SCHEMBL17585453 | 0.86 | PDGFRB (0.50) | PDGFRBPDGFRAALDH1A1F2GLA | |
| SCHEMBL7028923 | 0.85 | ALDH1A1 (0.70) | PDGFRBPDGFRAALDH1A1F2GLA | |
| SCHEMBL15041953 | 0.80 | ALDH1A1 (0.55) | PDGFRBPDGFRAALDH1A1F2GLA | |
| SCHEMBL21988953 | 0.79 | ALDH1A1 (0.71) | PDGFRBPDGFRAALDH1A1F2GLA | |
| SCHEMBL360304 | 0.79 | ALDH1A1 (0.54) | PDGFRBPDGFRAALDH1A1F2GLA | |
| SCHEMBL3839079 | 0.79 | ALDH1A1 (0.54) | PDGFRBPDGFRAALDH1A1F2GLA | |
| SCHEMBL620427 | 0.79 | ALDH1A1 (0.54) | PDGFRBPDGFRAALDH1A1F2GLA | |
| SCHEMBL620457 | 0.79 | ALDH1A1 (0.58) | PDGFRBPDGFRAALDH1A1F2GLA | |
| SCHEMBL3868339 | 0.78 | BACE1 (0.47) | PDGFRBPDGFRACYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685737-B2 | Fluorinated integrin antagonists | OCUTERRA THERAPEUTICS, INC. (US) | 2023-06-27 | — | — | US | disclosed |
| US-11685738-B2 | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof | OCUTERRA THERAPEUTICS, INC. (US) | 2023-06-27 | — | — | US | disclosed |
| US-20170369490-A1 | FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF | FELIQS CORPORATION (JP) | 2017-12-28 | — | — | US | disclosed |
| US-9790222-B2 | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-10-17 | — | — | US | disclosed |
| US-20170291900-A1 | FLUORINATED INTEGRIN ANTAGONISTS | FELIQS CORPORATION (JP) | 2017-10-12 | — | — | US | disclosed |
| US-9717729-B2 | Fluorinated integrin antagonists | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-08-01 | — | — | US | disclosed |
| US-20170071939-A1 | FLUORINATED INTEGRIN ANTAGONISTS | FELIQS CORPORATION (JP) | 2017-03-16 | — | — | US | disclosed |
| US-9518053-B2 | Fluorinated integrin antagonists | SCIFLUOR LIFE SCIENCES, INC. (US) | 2016-12-13 | — | — | US | disclosed |
| US-20160244447-A1 | FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF | FELIQS CORPORATION (JP) | 2016-08-25 | — | — | US | disclosed |
| US-20160075698-A1 | FLUORINATED INTEGRIN ANTAGONISTS | FELIQS CORPORATION (JP) | 2016-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685737-B2 | Fluorinated integrin antagonists | ITGB5, ITGB1, ITGA5 | PDGFRB 85/4885PDGFRA 200/4885ALDH1A1 2260/4885 |
| US-20170071939-A1 | FLUORINATED INTEGRIN ANTAGONISTS | ITGB5, ITGB1, ITGA5 | PDGFRB 85/4885PDGFRA 200/4885ALDH1A1 2260/4885 |
| US-20170369490-A1 | FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF | FFAR3, FFAR2, FFAR1 | PDGFRB 442/4885PDGFRA 614/4885ALDH1A1 1949/4885 |
| US-11685738-B2 | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof | FFAR3, FFAR2, FFAR1 | PDGFRB 442/4885PDGFRA 614/4885ALDH1A1 1949/4885 |
| US-20160244447-A1 | FLUORINATED TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID DERIVATIVES AND USES THEREOF | FFAR3, FFAR2, FFAR1 | PDGFRB 442/4885PDGFRA 614/4885ALDH1A1 1949/4885 |
| US-20160075698-A1 | FLUORINATED INTEGRIN ANTAGONISTS | ITGB5, ITGB1, ITGA5 | PDGFRB 85/4885PDGFRA 200/4885ALDH1A1 2260/4885 |
| US-20170291900-A1 | FLUORINATED INTEGRIN ANTAGONISTS | ITGB5, ITGB1, ITGA5 | PDGFRB 85/4885PDGFRA 200/4885ALDH1A1 2260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.