Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.64 |
| ▸ | TTR | P02766 | 1/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 14/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17585483 | 0.90 | PDPK1 (0.61) | PDPK1TTRALOX5ABCB1MAOB | |
| SCHEMBL16166366 | 0.90 | PDPK1 (0.61) | PDPK1TTRALOX5ABCB1MAOB | |
| SCHEMBL16174007 | 0.89 | PDPK1 (0.60) | PDPK1TTRALOX5ABCB1MAOB | |
| Hydrochloric Acid SCHEMBL16166341 | 0.89 | PDPK1 (0.60) | PDPK1TTRALOX5ABCB1MAOB | |
| SCHEMBL16174033 | 0.88 | PDPK1 (0.59) | PDPK1TTRALOX5ABCB1MAOB | |
| SCHEMBL30630233 | 0.88 | ABCB1 (0.62) | PDPK1TTRALOX5ABCB1MAOB | |
| SCHEMBL16174002 | 0.88 | PDPK1 (0.59) | PDPK1TTRALOX5ABCB1MAOB | |
| SCHEMBL16166501 | 0.87 | ALOX5 (0.58) | PDPK1TTRALOX5ABCB1MAOB | |
| SCHEMBL16166503 | 0.87 | ALOX5 (0.58) | PDPK1TTRALOX5ABCB1MAOB | |
| SCHEMBL18723168 | 0.87 | ALOX5 (0.58) | PDPK1TTRALOX5ABCB1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617213-B2 | Synthetic analogues of xanthohumol | UNIVERSITA' DI PISA (IT) | 2017-04-11 | — | — | US | disclosed |
| US-20160075652-A1 | SYNTHETIC ANALOGUES OF XANTHOHUMOL | AZIENDA OSPEDALIERA DI REGGIO EMILIA ARCISPEDALE S. MARIA NUOVA IRCCS (IT) | 2016-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075652-A1 | SYNTHETIC ANALOGUES OF XANTHOHUMOL | XDH, XPA, NR1H3 | PDPK1 3213/4885TTR 4577/4885ALOX5 1060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.