Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 16/20 | 0.44 |
| ▸ | PDE1A | P54750 | 6/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 6/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880851 | 0.83 | PDE5A (0.39) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL1758918 | 0.79 | PDE5A (0.44) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL1759205 | 0.74 | CNR2 (0.62) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL1758713 | 0.73 | PDE5A (0.54) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL1758649 | 0.72 | EPHX2 (0.63) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL1759195 | 0.69 | GAA (0.53) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL6880652 | 0.69 | PDE5A (0.47) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL1758738 | 0.67 | PDE5A (0.48) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL3607475 | 0.67 | PDE5A (0.70) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL1758817 | 0.67 | PDE5A (0.50) | PDE5APDE1APDE1BPDE1CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | claimed |
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | disclosed |