Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878631 | 0.84 | EPHX2 (0.42) | EPHX2NPC1MEN1KMT2ARAB9A | |
| SCHEMBL1758651 | 0.84 | LMNA (0.53) | EPHX2NPC1MEN1KMT2ARAB9A | |
| SCHEMBL10046724 | 0.82 | HDAC11 (0.56) | EPHX2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1758784 | 0.82 | NPC1 (0.48) | EPHX2NPC1MEN1KMT2ARAB9A | |
| SCHEMBL10046722 | 0.81 | HDAC11 (0.62) | EPHX2MEN1KMT2APOLBLMNA | |
| SCHEMBL10046723 | 0.80 | RARB (0.56) | EPHX2MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL8839036 | 0.76 | EPHX2 (0.54) | EPHX2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8839097 | 0.75 | S1PR1 (0.53) | EPHX2MEN1KMT2APOLBLMNA | |
| SCHEMBL4113212 | 0.73 | CYP4F2 (0.76) | NPC1KMT2ARAB9ACYP4F2CYP4A11 | |
| SCHEMBL3327170 | 0.72 | EPHX2 (0.53) | EPHX2NPC1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | disclosed |