Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6876907 | 0.86 | MEN1 (0.40) | MAPTNPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL1758644 | 0.84 | EPHX2 (0.56) | EPHX2MAPTCYP4F2CYP4A11RAB9A | |
| SCHEMBL6880231 | 0.74 | KDM1A (0.42) | EPHX2HRH3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6878609 | 0.74 | EPHX2 (0.41) | EPHX2MAPTCYP4F2CYP4A11RAB9A | |
| SCHEMBL6880849 | 0.73 | HDAC1 (0.50) | EPHX2MAPTNPC1GAASMN1; SMN2 | |
| SCHEMBL14755639 | 0.72 | MEN1 (0.41) | EPHX2HRH3RAB9ANPC1GAA | |
| SCHEMBL1758784 | 0.71 | NPC1 (0.48) | EPHX2RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8289283 | 0.70 | ALDH1A1 (0.38) | EPHX2MAPTRAB9ANPC1GAA | |
| SCHEMBL1758651 | 0.70 | LMNA (0.53) | EPHX2RAB9ANPC1GAASMN1; SMN2 | |
| SCHEMBL10046724 | 0.69 | HDAC11 (0.56) | EPHX2MAPTGAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | disclosed |