Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | TERT | O14746 | 3/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARD | Q03181 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758741 | 1.00 | FAAH (0.56) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL1758734 | 0.96 | ALDH1A1 (0.57) | FAAHCES1PPARGPPARDPPARA | |
| SCHEMBL1759035 | 0.91 | FAAH (0.48) | FAAHCES1PTPN1PPARGPPARD | |
| SCHEMBL31481970 | 0.89 | FAAH (0.61) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL3418506 | 0.89 | FAAH (0.61) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL3421715 | 0.89 | FAAH (0.61) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL3422826 | 0.89 | FAAH (0.61) | FAAHCES1TERTPTPN1PPARG | |
| SCHEMBL4371696 | 0.87 | PPARG (0.65) | FAAHTERTPTPN1PPARGPPARD | |
| SCHEMBL4371692 | 0.87 | PPARG (0.65) | FAAHTERTPTPN1PPARGPPARD | |
| Adipic Acid SCHEMBL28790872 | 0.85 | PPARG (0.68) | FAAHTERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056682-A1 | REVERSE HEAD GROUP LIPIDS, LIPID PARTICLE COMPOSITIONS COMPRISING REVERSE HEADGROUP LIPIDS, AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-05-12 | — | — | WO | disclosed |