Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758748 | 1.00 | MAPT (0.53) | MAPTALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL755100 | 0.89 | MAPT (0.52) | MAPTALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL755101 | 0.89 | MAPT (0.52) | MAPTALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL1758728 | 0.79 | MAPT (0.46) | MAPTALDH1A1HTTGAALMNA | |
| SCHEMBL3247481 | 0.77 | ALDH1A1 (0.57) | MAPTALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL3247484 | 0.77 | ALDH1A1 (0.57) | MAPTALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL8837891 | 0.77 | MAPT (0.67) | MAPTALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL8837893 | 0.77 | MAPT (0.67) | MAPTALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL15660603 | 0.76 | MAPT (0.51) | MAPTALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL15660601 | 0.76 | MAPT (0.51) | MAPTALDH1A1HPGDCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921360-B2 | Heterobicycle-substituted azolyl benzene fungicides | E. I. DU PONT DE NEMOURS AND COMPANY | 2014-12-30 | — | — | US | disclosed |
| EP-2493880-B1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | DU PONT (US) | 2013-09-18 | — | — | EP | disclosed |
| EP-2493880-A1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | E. I. du Pont de Nemours and Company (US) | 2012-09-05 | — | — | EP | disclosed |
| US-20120202815-A1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | E.I.DU PONT DE NEMOURS AND COMPANY (US) | 2012-08-09 | — | — | US | disclosed |
| WO-2011059619-A1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202815-A1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | CBR3, CBR1, CYP2S1 | MAPT 4549/4885ALDH1A1 3110/4885HPGD 4078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.