Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755100 | 1.00 | MAPT (0.52) | MAPTALDH1A1LMNAHPGDCYP1A2 | |
| SCHEMBL1758747 | 0.89 | MAPT (0.53) | MAPTALDH1A1LMNAHPGDCYP1A2 | |
| SCHEMBL1758748 | 0.89 | MAPT (0.53) | MAPTALDH1A1LMNAHPGDCYP1A2 | |
| SCHEMBL15660601 | 0.88 | MAPT (0.51) | MAPTALDH1A1LMNAHPGDCYP1A2 | |
| SCHEMBL15660603 | 0.88 | MAPT (0.51) | MAPTALDH1A1LMNAHPGDCYP1A2 | |
| SCHEMBL1758939 | 0.78 | TSHR (0.54) | MAPTALDH1A1LMNAHPGDHTT | |
| SCHEMBL4623289 | 0.78 | TSHR (0.54) | MAPTALDH1A1LMNAHPGDCYP1A2 | |
| SCHEMBL8837891 | 0.76 | MAPT (0.67) | MAPTALDH1A1LMNAHPGDCYP1A2 | |
| SCHEMBL8837893 | 0.76 | MAPT (0.67) | MAPTALDH1A1LMNAHPGDCYP1A2 | |
| SCHEMBL27779900 | 0.76 | THRA (0.48) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9743667-B2 | Substituted benzene fungicides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-08-29 | — | — | US | disclosed |
| EP-2430921-B1 | Substituted benzene fungicides | DU PONT (US) | 2017-07-05 | — | — | EP | disclosed |
| US-9198433-B2 | Substituted benzene fungicides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-12-01 | — | — | US | disclosed |
| US-20150335023-A1 | SUBSTITUTED BENZENE FUNGICIDES | FMC CORPORATION | 2015-11-26 | — | — | US | disclosed |
| US-8921360-B2 | Heterobicycle-substituted azolyl benzene fungicides | E. I. DU PONT DE NEMOURS AND COMPANY | 2014-12-30 | — | — | US | disclosed |
| US-20140323436-A1 | SUBSTITUTED BENZENE FUNGICIDES | FMC CORPORATION | 2014-10-30 | — | — | US | disclosed |
| US-8822521-B2 | Substituted benzene fungicides | E I DU PONT DE NEMOURS AND COMPANY (DE) | 2014-09-02 | — | — | US | disclosed |
| EP-2493880-B1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | DU PONT (US) | 2013-09-18 | — | — | EP | disclosed |
| EP-2493880-A1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | E. I. du Pont de Nemours and Company (US) | 2012-09-05 | — | — | EP | disclosed |
| US-20120202815-A1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | E.I.DU PONT DE NEMOURS AND COMPANY (US) | 2012-08-09 | — | — | US | disclosed |
| EP-2430921-A2 | Substituted benzene fungicides | E.I. Du Pont De Nemours And Company (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2011059619-A1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-19 | — | — | WO | disclosed |
| US-20100120714-A1 | SUBSTITUTED BENZENE FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-05-13 | — | — | US | disclosed |
| EP-2129225-A2 | SUBSTITUTED BENZENE FUNGICIDES | E. I. Du Pont de Nemours and Company (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008124092-A2 | SUBSTITUTED BENZENE FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202815-A1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | CBR3, CBR1, CYP2S1 | MAPT 4549/4885ALDH1A1 3110/4885LMNA 4756/4885 |
| US-20150335023-A1 | SUBSTITUTED BENZENE FUNGICIDES | NR0B1, CBR3, NR0B2 | MAPT 4627/4885ALDH1A1 2928/4885LMNA 4202/4885 |
| US-20140323436-A1 | SUBSTITUTED BENZENE FUNGICIDES | NR0B1, CBR3, NR0B2 | MAPT 4627/4885ALDH1A1 2928/4885LMNA 4202/4885 |
| US-20100120714-A1 | SUBSTITUTED BENZENE FUNGICIDES | NR0B1, CBR3, NR0B2 | MAPT 4633/4885ALDH1A1 3064/4885LMNA 4145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.