Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13278793 | 0.78 | PBRM1 (0.31) | PBRM1 | |
| SCHEMBL1395939 | 0.75 | HRH4 (0.32) | — | |
| SCHEMBL22470605 | 0.74 | KDM4C (0.37) | PBRM1 | |
| SCHEMBL92711 | 0.68 | HTR6 (0.43) | — | |
| SCHEMBL18480 | 0.68 | HTR6 (0.43) | — | |
| SCHEMBL18189054 | 0.68 | HTR6 (0.43) | — | |
| SCHEMBL9290791 | 0.68 | HTR6 (0.43) | — | |
| SCHEMBL780212 | 0.68 | HTR6 (0.43) | — | |
| SCHEMBL8166655 | 0.68 | HTR6 (0.43) | — | |
| SCHEMBL27467945 | 0.68 | HTR6 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120288443-A1 | LABELLED PYRROLYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR USE IN DIAGNOSTIC METHODS | NEUROSEARCH A/S (DK) | 2012-11-15 | — | — | US | claimed |
| EP-2498826-A1 | LABELLED PYRROLYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR USE IN DIAGNOSTIC METHODS | NeuroSearch AS (DK) | 2012-09-19 | — | — | EP | claimed |
| WO-2011058002-A1 | LABELLED PYRROLYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR USE IN DIAGNOSTIC METHODS | NEUROSEARCH A/S (DK) | 2011-05-19 | — | — | WO | claimed |
| US-8946412-B2 | Diazabicyclononyl oxadiazole compounds and their use as nicotinic acetylcholine receptor modulators | DANPET AB (SE) | 2015-02-03 | — | — | US | disclosed |
| US-20130004428-A1 | DIAZABICYCLONONYL OXADIAZOLE COMPOUNDS AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2013-01-03 | — | — | US | disclosed |
| US-20120288443-A1 | LABELLED PYRROLYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR USE IN DIAGNOSTIC METHODS | NEUROSEARCH A/S (DK) | 2012-11-15 | — | — | US | disclosed |
| EP-2513097-A1 | DIAZABICYCLONONYL OXADIAZOLE COMPOUNDS AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NeuroSearch AS (DK) | 2012-10-24 | — | — | EP | disclosed |
| EP-2498826-A1 | LABELLED PYRROLYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR USE IN DIAGNOSTIC METHODS | NeuroSearch AS (DK) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011073296-A1 | DIAZABICYCLONONYL OXADIAZOLE COMPOUNDS AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011058002-A1 | LABELLED PYRROLYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR USE IN DIAGNOSTIC METHODS | NEUROSEARCH A/S (DK) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120288443-A1 | LABELLED PYRROLYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR USE IN DIAGNOSTIC METHODS | GRM3, SSTR3, OXGR1 | PBRM1 2562/4885 |
| US-20130004428-A1 | DIAZABICYCLONONYL OXADIAZOLE COMPOUNDS AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | CHRNA3, CHRNA1, CHRNA5 | PBRM1 3513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.