SCHEMBL175889

SCHEMBL175889

C=CCc1ccc(Nc2ccc(CC=C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
CYP3A4 P08684 3/20 0.50
ALOX15 P16050 2/20 0.50
TSHR P16473 2/20 0.50
ALOX12 P18054 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TP53 P04637 1/20 0.50
XDH P47989 1/20 0.45
MAPT P10636 3/20 0.43
GABRA1 P14867 3/20 0.43
GABRB2 P47870 3/20 0.43
CNR2 P34972 3/20 0.43
PPARG P37231 2/20 0.43
PPARD Q03181 2/20 0.43
MEN1 O00255 2/20 0.43
GAA P10253 2/20 0.43
CNR1 P21554 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH2 P05091 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6406231 1.00 ALDH1A1 (0.50) ALDH1A1CYP3A4ALOX15TSHRALOX12
SCHEMBL3428485 0.93 ALDH1A1 (0.45) ALDH1A1CYP3A4ALOX15TSHRALOX12
SCHEMBL2582312 0.91 ALDH1A1 (0.54) ALDH1A1CYP3A4ALOX15TSHRALOX12
SCHEMBL28999966 0.89 ALDH1A1 (0.48) ALDH1A1CYP3A4ALOX15TSHRALOX12
SCHEMBL4614917 0.89 MEN1 (0.44) ALDH1A1CYP3A4ALOX15TSHRALOX12
Diphenylamine SCHEMBL7578440 0.84 HSD17B10 (0.52) ALDH1A1CYP3A4ALOX15TSHRALOX12
SCHEMBL173301 0.84 ALDH1A1 (0.64) ALDH1A1CYP3A4ALOX15TSHRALOX12
SCHEMBL1173026 0.82 ALDH1A1 (0.59) ALDH1A1CYP3A4ALOX15TSHRALOX12
SCHEMBL20149300 0.81 ALDH1A1 (0.52) ALDH1A1CYP3A4ALOX15TSHRALOX12
SCHEMBL2064722 0.81 ALDH1A1 (0.47) ALDH1A1CYP3A4ALOX15TSHRALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3020790-B1 TRUNK PISTON ENGINE OIL COMPOSITION FOR LOW SULFUR MARINE DISTILLATE FUELED ENGINES CHEVRON ORONITE TECH BV (NL) 2022-06-08 EP claimed
US-11208610-B2 Lubricant oil composition IDEMITSU KOSAN CO., LTD. (JP) 2021-12-28 US claimed
EP-3409750-B1 LUBRICANT OIL COMPOSITION IDEMITSU KOSAN CO (JP) 2020-08-19 EP claimed
CN-106916432-B For stablizing polyoxygenated alkene polyether polyol, the method for preventing its oxidative degradation 艾特国际有限公司 2019-07-19 CN claimed
US-20190024008-A1 LUBRICANT OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2019-01-24 US claimed
EP-3409750-A1 LUBRICANT OIL COMPOSITION Idemitsu Kosan Co., Ltd (JP) 2018-12-05 EP claimed
US-9758688-B2 Composition for forming conductive film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-12 US claimed
US-20160137949-A1 Low sulfur marine distillate fuel Trunk Piston Engine Oil composition. CHEVRON ORONITE TECHNOLOGY B.V. (US) 2016-05-19 US claimed
EP-0644922-B2 FUNCTIONAL FLUID SOLUTIA INC (US) 2007-06-13 EP claimed
JP-3420235-B2 2003-06-23 JP claimed
EP-0644922-B1 FUNCTIONAL FLUID MONSANTO CO (US) 1998-05-13 EP claimed
US-5464551-A Aircraft hydraulic fluid MONSANTO COMPANY (US) 1995-11-07 US claimed
EP-0644922-A1 FUNCTIONAL FLUID MONSANTO COMPANY (US) 1995-03-29 EP claimed
WO-1993025641-A1 FUNCTIONAL FLUID MONSANTO COMPANY (US) 1993-12-23 WO claimed
EP-0460317-B1 Polyalkylene glycol lubricant compositions ETHYL PETROLEUM ADDITIVES LTD (GB) 1993-10-20 EP claimed
EP-0456925-B1 Antioxidant compositions ETHYL PETROLEUM ADDITIVES LTD (GB) 1993-10-20 EP claimed
EP-0456925-A1 Antioxidant compositions ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1991-11-21 EP claimed
EP-0294045-B1 AMINE COMPATIBILITY AIDS IN LUBRICATING OIL COMPOSITIONS EXXON CHEMICAL PATENTS INC. (US) 1990-11-07 EP claimed
EP-0294045-A2 Amine compatibility aids in lubricating oil compositions EXXON CHEMICAL PATENTS INC. (US) 1988-12-07 EP claimed
US-4130494-A ESTER, AMINE PHOSPHATE SALT EXXON RESEARCH & ENGINEERING CO. (US) 1978-12-19 US claimed